Journal article
Treadmill measures of ambulation rates in ovine models of spinal cord injury and neuropathic pain
Journal of medical engineering & technology, Vol.40(3), pp.72-79
04/02/2016
DOI: 10.3109/03091902.2015.1132786
PMID: 26785329
Abstract
Our laboratories are developing treadmill-based gait analysis employing sheep to investigate potential efficacy of intra-dural spinal cord stimulation in the treatment of spinal cord injury and neuropathic pain. As part of efforts to establish the performance characteristics of the experimental arrangement, this study measured the treadmill speed via a tachometer, video belt-marker timing and ambulation-rate observations of the sheep. The data reveal a 0.1-0.3% residual drift in the baseline (unloaded) treadmill speed which increases with loading, but all three approaches agree on final speed to within 1.7%, at belt speeds of ≈4 km/h. Using the tachometer as the standard, the estimated upper limit on uncertainty in the video belt-marker approach is ± 0.18 km h
−1
and the measured uncertainty is ± 0.15 km h
−1
. Employment of the latter method in determining timing differences between contralateral hoof strikes by the sheep suggests its utility in assessing severity of SCI and responses to therapeutic interventions.
Details
- Title: Subtitle
- Treadmill measures of ambulation rates in ovine models of spinal cord injury and neuropathic pain
- Creators
- S Safayi - Department of Veterinary Clinical Sciences, Iowa State UniversityJ. W Miller - Department of Neurosurgery, University of Iowa Hospitals and ClinicsS Wilson - Department of Neurosurgery, University of Iowa Hospitals and ClinicsS. K Shivapour - Department of Veterinary Clinical Sciences, Iowa State UniversityT. F Oelfke - Department of Veterinary Clinical Sciences, Iowa State UniversityA. L Ford - Department of Veterinary Clinical Sciences, Iowa State UniversityA Klarmann Staudt - Department of Veterinary Clinical Sciences, Iowa State UniversityK Abode-Iyamah - Department of Neurosurgery, University of Iowa Hospitals and ClinicsC. G Reddy - Department of Neurosurgery, University of Iowa Hospitals and ClinicsN. D Jeffery - Department of Veterinary Clinical Sciences, Iowa State UniversityD. C Fredericks - Department of Orthopaedics & Rehabilitation, University of Iowa Hospitals and ClinicsG. T Gillies - Department of Mechanical and Aerospace Engineering, University of VirginiaM A Howard III - Department of Neurosurgery, University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of medical engineering & technology, Vol.40(3), pp.72-79
- DOI
- 10.3109/03091902.2015.1132786
- PMID
- 26785329
- NLM abbreviation
- J Med Eng Technol
- ISSN
- 0309-1902
- eISSN
- 1464-522X
- Publisher
- Taylor & Francis
- Language
- English
- Date published
- 04/02/2016
- Academic Unit
- Neurology; Electrical and Computer Engineering; Iowa Neuroscience Institute; Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center; Neurosurgery; Otolaryngology
- Record Identifier
- 9984015838902771
Metrics
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