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Treatment Options: Biological Basis of Regenerative Endodontic Procedures
Journal article   Open access   Peer reviewed

Treatment Options: Biological Basis of Regenerative Endodontic Procedures

Kenneth M Hargreaves, Anibal Diogenes and Fabricio B Teixeira
Journal of endodontics, Vol.39(3), pp.S30-S43
03/2013
DOI: 10.1016/j.joen.2012.11.025
PMCID: PMC3589799
PMID: 23439043
url
https://doi.org/10.1016/j.joen.2012.11.025View
Published (Version of record) Open Access

Abstract

Dental trauma occurs frequently in children and often can lead to pulpal necrosis. The occurrence of pulpal necrosis in the permanent but immature tooth represents a challenging clinical situation because the thin and often short roots increase the risk of subsequent fracture. Current approaches for treating the traumatized immature tooth with pulpal necrosis do not reliably achieve the desired clinical outcomes, consisting of healing of apical periodontitis, promotion of continued root development, and restoration of the functional competence of pulpal tissue. An optimal approach for treating the immature permanent tooth with a necrotic pulp would be to regenerate functional pulpal tissue. This review summarizes the current literature supporting a biological rationale for considering regenerative endodontic treatment procedures in treating the immature permanent tooth with pulp necrosis.
trauma stem cells regenerative endodontics Children pulpal revascularization

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