Journal article
Treatment approaches to prosthetic joint infections: results of an Emerging Infections Network survey
Diagnostic microbiology and infectious disease, Vol.66(1), pp.16-23
2010
DOI: 10.1016/j.diagmicrobio.2009.08.016
PMID: 19782494
Abstract
We report the results of an Emerging Infections Network survey of 994 infectious disease consultants (IDCs) regarding their participation in the medical management of prosthetic joint infections and observations of adverse effects associated with antibiotic-impregnated materials (response rate, 54.8%). There was general agreement about when a prosthesis can be retained, but substantial variability in the duration of suppressive antibiotics was recommended, with 36% supporting life-long suppression. For 2-stage procedures, 95% recommended a minimum of 4 weeks of systemic antibiotics after the first stage. However, there was little agreement regarding the duration of an antibiotic-free period before reimplantation. Eleven percent of IDCs reported adverse events related to antibiotic-impregnated materials, ranging from skin reactions to renal failure. Further studies to address the substantial variability in the duration of antibiotic suppressive therapy for retained joints and for the duration of antibiotic-free period before reimplantation are needed.
Details
- Title: Subtitle
- Treatment approaches to prosthetic joint infections: results of an Emerging Infections Network survey
- Creators
- Birgir Johannsson - Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USAJames Taylor - University of IowaCharles R Clark - Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USAHala Shamsuddin - Department of Health and Human Services, United States Food and Drug Administration, Silver Spring, MD 20993, USASusan E Beekmann - Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USAPhilip Polgreen - Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Diagnostic microbiology and infectious disease, Vol.66(1), pp.16-23
- DOI
- 10.1016/j.diagmicrobio.2009.08.016
- PMID
- 19782494
- NLM abbreviation
- Diagn Microbiol Infect Dis
- ISSN
- 0732-8893
- eISSN
- 1879-0070
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 2010
- Academic Unit
- Infectious Diseases; Epidemiology; Orthopedics and Rehabilitation; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984040317402771
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