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Treatment of Acutely Ruptured Cerebral Aneurysms With the Woven EndoBridge Device: Experience Post-FDA Approval
Journal article   Open access   Peer reviewed

Treatment of Acutely Ruptured Cerebral Aneurysms With the Woven EndoBridge Device: Experience Post-FDA Approval

Fadi Al Saiegh, David Hasan, Nikolaos Mouchtouris, Mario Zanaty, Ahmad Sweid, Omaditya Khanna, Nohra Chalouhi, Ritam Ghosh, Stavropoula Tjoumakaris, M Reid Gooch, …
Neurosurgery, Vol.87(1), pp.E16-E22
07/01/2020
DOI: 10.1093/neuros/nyaa092
PMCID: PMC8929032
PMID: 32357228
url
https://doi.org/10.1093/neuros/nyaa092View
Published (Version of record) Open Access

Abstract

Coil embolization of ruptured bifurcation aneurysms is challenging and often necessitates adjunctive stenting, which requires antiplatelet therapy in the setting of subarachnoid hemorrhage (SAH). The Woven EndoBridge (WEB; Terumo) device is an alternative self-expanding 3D mesh that does not require antiplatelet agents. However, its use has been mostly reserved for unruptured aneurysms. To assess the safety and feasibility of ruptured aneurysm treatment with the WEB. Retrospective analysis of 9 SAH patients with 11 aneurysms that were treated with the WEB device at 2 institutions after FDA approval. Hunt and Hess grades were III and IV in 4 (44%) each and V in 1 (11%). All patients were treated within 24 h of hospitalization, and a single WEB was used in all but one aneurysm. Aneurysms treated were 3 basilar tip, 2 anterior communicating artery, 2 posterior inferior cerebellarartery, 1 middle cerebral artery, 1 carotid-ophthalmic artery, 1 posterior communicating artery, and 1 vertebrobasilar junction. Mean aneurysm height and width were 6.2 ± 2.2 mm (range: 3-10) and 5.6 ± 3.0 mm (range: 3.3-14), respectively. Mean dome-to-neck ratio was 1.7 ± 0.8 (range: 1.0-3.8). There was one intraoperative rupture that occurred because of device dislodgement and was managed with embolization. There were no treatment-related mortalities and no re-rupture after securement of the aneurysms with the WEB. Our preliminary experience indicates that the WEB device can be used safely for ruptured aneurysms of various sizes in the anterior and posterior circulation. Larger series with long-term follow-up are necessary to confirm our findings.
 Aged Aged, 80 and over Aneurysm, Ruptured - therapy Blood Vessel Prosthesis Embolization, Therapeutic - instrumentation Endovascular Procedures - instrumentation Female Humans Intracranial Aneurysm - therapy Male Middle Aged Retrospective Studies Stents Treatment Outcome

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