Treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: synopsis of the 2013 American College of Cardiology/American Heart Association cholesterol guideline

Neil J Stone; Jennifer G Robinson; Alice H Lichtenstein; David C Goff Jr; Donald M Lloyd-Jones; Sidney C Smith Jr; Conrad Blum; J Sanford Schwartz

doi:10.7326/M14-0126

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Treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: synopsis of the 2013 American College of Cardiology/American Heart Association cholesterol guideline

Journal article

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Peer reviewed

Treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: synopsis of the 2013 American College of Cardiology/American Heart Association cholesterol guideline

Neil J Stone, Jennifer G Robinson, Alice H Lichtenstein, David C Goff Jr, Donald M Lloyd-Jones, Sidney C Smith Jr, Conrad Blum and J Sanford Schwartz

Annals of internal medicine, Vol.160(5), pp.339-343

03/04/2014

DOI: 10.7326/M14-0126

PMID: 24474185

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Abstract

In November 2013, the American College of Cardiology and American Heart Association (ACC/AHA) released a clinical practice guideline on the treatment of blood cholesterol to reduce cardiovascular risk in adults. This synopsis summarizes the major recommendations. In 2008, the National Heart, Lung, and Blood Institute convened the Adult Treatment Panel (ATP) IV to update the 2001 ATP-III cholesterol guidelines using a rigorous process to systematically review randomized, controlled trials (RCTs) and meta-analyses of RCTs that examined cardiovascular outcomes. The panel commissioned independent systematic evidence reviews on low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol goals in secondary and primary prevention and the effect of lipid drugs on atherosclerotic cardiovascular disease events and adverse effects. In September 2013, the panel's draft recommendations were transitioned to the ACC/AHA. This synopsis summarizes key features of the guidelines in 8 areas: lifestyle, groups shown to benefit from statins, statin safety, decision making, estimation of cardiovascular disease risk, intensity of statin therapy, treatment targets, and monitoring of statin therapy.

Hypercholesterolemia - blood

Life Style

Monitoring, Physiologic

Humans

Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use

Risk Factors

Coronary Artery Disease - prevention & control

Cholesterol, HDL - blood

Cholesterol, LDL - blood

Hypercholesterolemia - drug therapy

Details

Title: Subtitle: Treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: synopsis of the 2013 American College of Cardiology/American Heart Association cholesterol guideline
Creators: Neil J Stone
Jennifer G Robinson
Alice H Lichtenstein
David C Goff Jr
Donald M Lloyd-Jones
Sidney C Smith Jr
Conrad Blum
J Sanford Schwartz
Contributors: 2013 ACC/AHA Cholesterol Guideline Panel
Resource Type: Journal article
Publication Details: Annals of internal medicine, Vol.160(5), pp.339-343
DOI: 10.7326/M14-0126
PMID: 24474185
NLM abbreviation: Ann Intern Med
ISSN: 1539-3704
eISSN: 1539-3704
Publisher: United States
Language: English
Date published: 03/04/2014
Academic Unit: Epidemiology; Internal Medicine
Record Identifier: 9983995047302771

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