Treatment selection in oropharyngeal cancer: a surveillance, epidemiology, and end results (SEER) patterns of care analysis

Nitin A Pagedar; Catherine Chioreso; Jennifer A Schlichting; Charles F Lynch; Mary E Charlton

doi:10.1007/s10552-017-0938-3

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Treatment selection in oropharyngeal cancer: a surveillance, epidemiology, and end results (SEER) patterns of care analysis

Journal article

Peer reviewed

Treatment selection in oropharyngeal cancer: a surveillance, epidemiology, and end results (SEER) patterns of care analysis

Nitin A Pagedar, Catherine Chioreso, Jennifer A Schlichting, Charles F Lynch and Mary E Charlton

Cancer causes & control, Vol.28(10), pp.1085-1093

10/2017

DOI: 10.1007/s10552-017-0938-3

PMCID: PMC5771802

PMID: 28815336

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https://www.ncbi.nlm.nih.gov/pmc/articles/5771802View

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Abstract

Treatment for oropharyngeal cancer (OPC) has changed over the past two decades under multiple influences. We provide a population-based description of the application of radiotherapy, surgery, and chemotherapy to OPC in 1997, 2004, and 2009. The National Cancer Institute's Patterns of Care study for OPC included multiple variables not available in the public-use dataset. We identified factors correlating with selection of primary surgery versus radiotherapy with or without chemotherapy (RTC) and analyzed predictors of all-cause mortality. We estimated the frequency of human papillomavirus (HPV) testing. RTC was more common in 2009 than in 1997, and was more commonly applied to Stage IV cases. However, RTC was not an independent risk factor for mortality compared with surgery. HPV status was known in 14% of patients in 2009. RTC is the most common treatment for OPC, but it may not provide the best outcomes. HPV testing was uncommon in 2009.

Oropharyngeal Neoplasms - therapy

SEER Program

Humans

Middle Aged

Papillomavirus Infections - epidemiology

Risk Factors

Male

Oropharyngeal Neoplasms - virology

Oropharyngeal Neoplasms - epidemiology

Delivery of Health Care

Adult

Female

Papillomaviridae

Papillomavirus Infections - virology

Aged

Details

Title: Subtitle: Treatment selection in oropharyngeal cancer: a surveillance, epidemiology, and end results (SEER) patterns of care analysis
Creators: Nitin A Pagedar - Department of Otolaryngology - Head and Neck Surgery, University of Iowa, 200 Hawkins Drive, 21200 PFP, Iowa City, IA, 52242, USA. nitin-pagedar@uiowa.edu
Catherine Chioreso - Department of Epidemiology, University of Iowa, Iowa City, IA, USA
Jennifer A Schlichting - Department of Epidemiology, University of Iowa, Iowa City, IA, USA
Charles F Lynch - State Health Registry of Iowa, Iowa City, IA, USA
Mary E Charlton - Department of Epidemiology, University of Iowa, Iowa City, IA, USA
Resource Type: Journal article
Publication Details: Cancer causes & control, Vol.28(10), pp.1085-1093
DOI: 10.1007/s10552-017-0938-3
PMID: 28815336
PMCID: PMC5771802
NLM abbreviation: Cancer Causes Control
ISSN: 0957-5243
eISSN: 1573-7225
Publisher: Netherlands
Grant note: HHSN26100006 / National Cancer Institute P30CA086862 / National Cancer Institute (US) HHSN261201300020I / National Cancer Institute HHSN261201300020I / NCI NIH HHS P30 CA086862 / NCI NIH HHS
Language: English
Date published: 10/2017
Academic Unit: Health Management and Policy; Epidemiology; Otolaryngology
Record Identifier: 9983996064602771

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