Journal article
Trends in Hospitalization Rates, Major Causes of Hospitalization, and In‐Hospital Mortality in Rheumatoid Arthritis in the United States From 2000 to 2014
ACR open rheumatology, Vol.2(12), pp.715-724
12/2020
DOI: 10.1002/acr2.11200
PMCID: PMC7738807
PMID: 33215872
Abstract
Objective
To evaluate national trends in hospitalizations and in‐hospital mortality in rheumatoid arthritis (RA).
Methods
National Inpatient Sample from 2000‐2014 and United States Census data were used to study temporal trends in adult RA hospitalizations, reasons for hospitalizations, and in‐hospital mortality.
Results
The data represented 183 983 hospitalizations with a primary diagnosis of RA. The annual rates of hospitalization for the primary diagnosis of RA decreased from 76.54 admissions per 1 million in 2000 to 29.96 per 1 million in 2014 (P trend < 0.0001). The hospital mortality rate declined from 0.70% to 0.41% (P trend < 0.0001) in this group. With a primary or nonprimary diagnosis of RA, the mortality rate ranged between 1.95 and 2.87 (P trend 0.08). For a nonprimary diagnosis of RA, we noted that the proportion of hospitalizations with a diagnosis of myocardial infarction (6.4% in 2000 to 4.6% in 2014; P < 0.001) significantly decreased, but the absolute number of hospitalizations significantly increased. In contrast, the proportion and the absolute number of hospitalizations with any diagnosis of sepsis, congestive heart failure, lung disease, and urinary tract infection increased significantly. We also noted a significant increase in the actual rate and proportions for hospitalizations for hip and knee arthroplasty. Among in‐hospital deaths when RA was a nonprimary diagnosis, the most common primary diagnosis was pneumonia (12.5 %) in 2000, whereas sepsis accounted for the most deaths in 2014 (31.4%).
Conclusion
We observed that hospitalization rates and in‐hospital mortality rates in patients with RA have changed significantly over the past 15 years.
Details
- Title: Subtitle
- Trends in Hospitalization Rates, Major Causes of Hospitalization, and In‐Hospital Mortality in Rheumatoid Arthritis in the United States From 2000 to 2014
- Creators
- Priyanka Iyer - University of California at Irvine Medical CenterYubo Gao - Iowa City Veteran’s Affairs Medical Center, and University of IowaElizabeth H Field - University of IowaJeffrey R Curtis - University of Alabama at BirminghamCharles F Lynch - University of IowaMary Vaughan‐Sarrazin - Iowa City Veteran’s Affairs Medical Center, and University of IowaNamrata Singh - University of Washington
- Resource Type
- Journal article
- Publication Details
- ACR open rheumatology, Vol.2(12), pp.715-724
- DOI
- 10.1002/acr2.11200
- PMID
- 33215872
- PMCID
- PMC7738807
- ISSN
- 2578-5745
- eISSN
- 2578-5745
- Number of pages
- 10
- Grant note
- Rheumatology Research Foundation
- Language
- English
- Date published
- 12/2020
- Academic Unit
- Health Management and Policy; Epidemiology; Immunology; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984214675402771
Metrics
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