Trends in aEEG Cyclicity and Amplitudes During Transition in Extremely Low Gestational Age Infants

Poorva Deshpande; Julia Dirks; Amish Jain; Patrick J McNamara; Cecil Hahn; Prakesh S Shah; Anne-Marie Guerguerian

doi:10.1111/apa.16761

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Trends in aEEG Cyclicity and Amplitudes During Transition in Extremely Low Gestational Age Infants

Journal article

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Trends in aEEG Cyclicity and Amplitudes During Transition in Extremely Low Gestational Age Infants

Poorva Deshpande, Julia Dirks, Amish Jain, Patrick J McNamara, Cecil Hahn, Prakesh S Shah and Anne-Marie Guerguerian

Acta paediatrica (Oslo, Norway : 1992), Vol.112(6), pp.1213-1219

06/2023

DOI: 10.1111/apa.16761

PMID: 36938912

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Abstract

To describe aEEG cyclicity, background pattern, voltage margins and maturation scores in extremely low gestational age neonates (ELGANs) in the first 72 hours. Fifty infants with gestational age (GA) 23 - 27 weeks were prospectively studied. Infants with intraventricular hemorrhage ≦ Grade I and no disorders of transition [persistent pulmonary hypertension, hypotension, pulmonary hemorrhage] belonged to the 'Uncomplicated' group and those with intraventricular hemorrhage > Grade I and/or disorders of transition, to the 'Complicated' group. Thirty-six infants without opioid exposure were included: 23 with GA 25.9 (23.1-27.7) weeks in the 'Uncomplicated' group and 13 with GA 24.6 (23.3-27.4) weeks in the 'Complicated' group. Cyclicity was more common in the 'Uncomplicated' group [20/ 23 (87%) vs. 7/13 (54%), p=0.045] with more cycles/hour [0.2 (0-0.78) vs. 0.03 (0-67), p=0.036]. Age at appearance of cyclicity were similar [20 (7.7- 40.7) hours in 'Uncomplicated' vs. 23.7 (5.4-60) hours in 'Complicated' group, p=0.8]. In the 'Uncomplicated' group, maturation scores (p=0.02), high (p<0.0001) and low (p=0.03) base voltage increased over time. During the first 72 hours, clinically stable ELGANs without neurological injury demonstrate increased cyclicity compared to those with a complicated course. Maturation score, high and low base voltage increase over time.

Neonates

ELGANs

Amplitude-Integrated Electroencephalography

Details

Title: Subtitle: Trends in aEEG Cyclicity and Amplitudes During Transition in Extremely Low Gestational Age Infants
Creators: Poorva Deshpande - University of Toronto
Julia Dirks - Neurosciences and Mental Health Program
Amish Jain - University of Toronto
Patrick J McNamara - Neurosciences and Mental Health Program
Cecil Hahn - Neurosciences and Mental Health Program
Prakesh S Shah - University of Toronto
Anne-Marie Guerguerian - Neurosciences and Mental Health Program
Resource Type: Journal article
Publication Details: Acta paediatrica (Oslo, Norway : 1992), Vol.112(6), pp.1213-1219
DOI: 10.1111/apa.16761
PMID: 36938912
NLM abbreviation: Acta Paediatr
ISSN: 0803-5253
eISSN: 1651-2227
Language: English
Electronic publication date: 03/20/2023
Date published: 06/2023
Academic Unit: Stead Family Department of Pediatrics; Neonatology; Internal Medicine
Record Identifier: 9984380373002771

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