Trends in the rates of hospitalizations for acute stroke among patients over 90 years of age with atrial fibrillation in the United States: from 2005 to 2014

Ghanshyam P. S. Shantha; Amgad Mentias; Musab Alqasrawi; Abdul Qazi; Chakradhari Inampudi; Kongkiat Chaikriangkrai; Abhishek Deshmuk; Steven Bailin; Michael Giudici; Alexander Mazur

doi:10.11909/j.issn.1671-5411.2017.09.002

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Trends in the rates of hospitalizations for acute stroke among patients over 90 years of age with atrial fibrillation in the United States: from 2005 to 2014

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Trends in the rates of hospitalizations for acute stroke among patients over 90 years of age with atrial fibrillation in the United States: from 2005 to 2014

Ghanshyam P. S. Shantha, Amgad Mentias, Musab Alqasrawi, Abdul Qazi, Chakradhari Inampudi, Kongkiat Chaikriangkrai, Abhishek Deshmuk, Steven Bailin, Michael Giudici and Alexander Mazur

Journal of geriatric cardiology : JGC, Vol.14(9), pp.547-552

01/01/2017

DOI: 10.11909/j.issn.1671-5411.2017.09.002

PMCID: PMC5641641

PMID: 29056954

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641641/View

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Abstract

Background Acute stroke (AS) rates in patients over 90 years of age (very elderly) with atrial fibrillation (AF) in the United States (US) are not known. We assessed trends in hospitalizations for AS among very elderly with AF in the US from 2005 to 2014. Methods We used the nationwide inpatient sample (NIS) from the USA; 2005-2014. AF and AS diagnoses were abstracted using international classification of diseases, 9(th) Revision, clinical modification (ICD-9-CM) codes. Results From 2005 to 2014, 3,606,073 hospitalizations of very elderly with AF were reported. Of these, 188,948 hospitalizations (141,822 hospitalizations in women and 47,126 hospitalizations in men) had AS as the primary diagnosis. Age adjusted AS hospitalizations increased in the total cohort (3217/million in 2005 to 3871/million in 2014), in women (3540/million in 2005 to 4487/million in 2014) and in men (2490/million in 2005 to 3173/million in 2014) (P< 0.001). Anticoagulation rates increased in women (8% in 2005 to 19.9% in 2014) and in men (8.9% in 2005 to 21.6% in 2014). AS rates, though numerically lower than the total cohort, showed an increasing trend in anticoagulated patients as well (all anticoagulated patients: 212/million in 2005 to 513/million in 2014; anticoagulated women: 224/million in 2005 to 529/million in 2014, anticoagulated men: 184/million in 2005 to 518/million in 2014). Conclusions There is an increasing trend in AS hospitalizations among nonagenarians with AF in the US despite improving utilization of anticoagulants in this patient population. The etiologies driving this alarming trend are unclear and require further study.

Cardiac & Cardiovascular Systems

Cardiovascular System & Cardiology

Geriatrics & Gerontology

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: Trends in the rates of hospitalizations for acute stroke among patients over 90 years of age with atrial fibrillation in the United States: from 2005 to 2014
Creators: Ghanshyam P. S. Shantha - University of Iowa Hospitals and Clinics
Amgad Mentias - Mayo CLinic, Rochester, MN, USA,
Musab Alqasrawi - University of Iowa
Abdul Qazi - University of Iowa
Chakradhari Inampudi - University of Iowa Hospitals and Clinics
Kongkiat Chaikriangkrai - University of Iowa Hospitals and Clinics
Abhishek Deshmuk - Mayo CLinic, Rochester, MN, USA,
Steven Bailin - University of Iowa Hospitals and Clinics
Michael Giudici - University of Iowa
Alexander Mazur - University of Iowa Hospitals and Clinics
Resource Type: Journal article
Publication Details: Journal of geriatric cardiology : JGC, Vol.14(9), pp.547-552
Publisher: Science Press
DOI: 10.11909/j.issn.1671-5411.2017.09.002
PMID: 29056954
PMCID: PMC5641641
ISSN: 1671-5411
Number of pages: 6
Language: English
Date published: 01/01/2017
Academic Unit: Cardiovascular Medicine; Internal Medicine
Record Identifier: 9984359835602771

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