Journal article
Trends with corticosteroid use in males with Duchenne muscular dystrophy born 1982-2001
Journal of child neurology, Vol.30(1), pp.21-26
01/2015
DOI: 10.1177/0883073813517263
PMID: 24682290
Abstract
This study examines trends in corticosteroid use for males with Duchenne muscular dystrophy by birth year, race/ethnicity, and knowledge of Duchenne muscular dystrophy family history. Firstborn males (n = 521) selected from a population-based surveillance system of Duchenne muscular dystrophy were analyzed using Kaplan Meier and regression methods. Comparing males born 1982 to 1986 with males born 1997 to 2001, steroid use increased from 54% to 72% and mean age at steroid initiation decreased from 8.2 to 7.1 years. Hispanics and non-Hispanic Black males used steroids less frequently and delayed initiation compared to white males. Compared to males without a Duchenne muscular dystrophy family history, males with known family history were half as likely to use steroids. Duration of steroid use increased over time and age at initiation decreased. Racial/ethnic disparities exist for steroid use and should be addressed to improve outcome and quality of life for boys with Duchenne muscular dystrophy.
Details
- Title: Subtitle
- Trends with corticosteroid use in males with Duchenne muscular dystrophy born 1982-2001
- Creators
- Deborah J Fox - New York State Department of Health, Albany, NY, USA djf03@health.state.ny.usAnil Kumar - New York State Department of Health, Albany, NY, USANancy A West - Department of Epidemiology, University of Colorado School of Public Health, Aurora, CO, USAA Gregory DiRienzo - Department of Epidemiology and Biostatistics, State University of New York at Albany, Rensselaer, NY, USAKatherine A James - Colorado Department of Public Health and Environment, Denver, CO, USAJoyce Oleszek - Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, CO, USAMuscular Dystrophy Surveillance, Tracking, and Research Network (MD STARnet)
- Contributors
- Paul A Romitti (Contributor) - University of Iowa, Epidemiology
- Resource Type
- Journal article
- Publication Details
- Journal of child neurology, Vol.30(1), pp.21-26
- DOI
- 10.1177/0883073813517263
- PMID
- 24682290
- ISSN
- 0883-0738
- eISSN
- 1708-8283
- Language
- English
- Date published
- 01/2015
- Academic Unit
- Epidemiology; Biostatistics
- Record Identifier
- 9984214693702771
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