Journal article
Trichoblastoma, syringocystadenoma papilliferum, desmoplastic trichilemmoma and tumor of the follicular infundibulum with signet-ring cells, all arising in nevus sebaceus
Journal of cutaneous pathology, Vol.42(9), pp.645-651
09/2015
DOI: 10.1111/cup.12489
PMID: 25761672
Abstract
Herein, we describe a 63-year-old male with multiple tumors arising within a nevus sebaceus on the posterior scalp. On histopathologic examination, four distinct tumors were identified: trichoblastoma, syringocystadenoma papilliferum, desmoplastic trichilemmoma and tumor of the follicular infundibulum (TFI). Within the TFI component of the nevus sebaceus, there was intracytoplasmic accumulation of eosinophilic keratin, as shown on pancytokeratin-stained sections, imparting a signet-ring appearance to the cells. To our knowledge, this is the first report of signet-ring cells arising within a TFI occurring in a nevus sebaceus. We discuss this case as well as review the literature on multiple tumors arising within nevus sebaceus and signet-ring cell changes in primary cutaneous tumors.
Details
- Title: Subtitle
- Trichoblastoma, syringocystadenoma papilliferum, desmoplastic trichilemmoma and tumor of the follicular infundibulum with signet-ring cells, all arising in nevus sebaceus
- Creators
- Emilie Dore - Carver College of Medicine, University of Iowa, Iowa City, IA, USAMegan H Noe - Department of Dermatology, University of Iowa, Iowa City, IA, USABrian L Swick - Department of Pathology, Iowa City Veterans Affairs Medical Center, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Journal of cutaneous pathology, Vol.42(9), pp.645-651
- Publisher
- United States
- DOI
- 10.1111/cup.12489
- PMID
- 25761672
- ISSN
- 0303-6987
- eISSN
- 1600-0560
- Language
- English
- Date published
- 09/2015
- Academic Unit
- Dermatology; Pathology
- Record Identifier
- 9984025475202771
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