Journal article
Trichophyton fungal keratitis
Cornea, Vol.25(1), pp.118-122
01/2006
DOI: 10.1097/01.ico.0000164834.77291.51
PMID: 16331054
Abstract
To report 5 cases of fungal keratitis caused by Trichophyton schoenleinii. Case reports. Trichophyton schoenleinii is responsible for aggressive fungal keratitis that is associated with keratolysis as a result of collagenase expression by the organism. Clinically, the organism seems to be sensitive to topical natamycin but resistant to topical amphotericin B and miconazole. Two patients achieved clinical cures with medical therapy alone, but with visual outcomes of only 20/125 and hand motions because of corneal scarring. Two patients achieved clinical cures with therapeutic penetrating keratoplasty (PKP), which remained clear and provided final visual outcomes of 20/60 and 20/200. One patient developed fungal scleritis and panophthalmitis despite 2 therapeutic PKPs and required enucleation. Trichophyton schoenleinii is a rare cause of fungal keratitis that may be associated with progressive keratolysis and perforation, scleral extension, and endophthalmitis. Therapeutic keratoplasty may be successful in achieving cure in medically unresponsive cases.
Details
- Title: Subtitle
- Trichophyton fungal keratitis
- Creators
- Abdulkarim Mohammad - Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi ArabiaAbdulaziz Al-RajhiMichael D Wagoner
- Resource Type
- Journal article
- Publication Details
- Cornea, Vol.25(1), pp.118-122
- Publisher
- United States
- DOI
- 10.1097/01.ico.0000164834.77291.51
- PMID
- 16331054
- ISSN
- 0277-3740
- eISSN
- 1536-4798
- Language
- English
- Date published
- 01/2006
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9983980045802771
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