Tuberculous cranial pachymeningitis

M J Thurtell; A B R Keed; M Yan; T Gottlieb; J M Spies; G M Halmagyi

doi:10.1212/01.wnl.0000252367.99393.34

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Journal article

Peer reviewed

Tuberculous cranial pachymeningitis

M J Thurtell, A B R Keed, M Yan, T Gottlieb, J M Spies and G M Halmagyi

Neurology, Vol.68(4), pp.298-300

01/23/2007

DOI: 10.1212/01.wnl.0000252367.99393.34

PMID: 17242338

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Abstract

We describe two immunocompetent patients with tuberculous cranial pachymeningitis. Both patients underwent biopsy after focal dural thickening was identified on MRI. Histopathologic examination of tissue revealed necrotizing granulomatous inflammation. PCR for Mycobacterium tuberculosis DNA was negative on CSF but positive on tissue. Both patients responded to antituberculous therapy. Although uncommon as a cause of cranial pachymeningitis, tuberculosis should be considered, since it responds well to treatment.

Radiography

Dura Mater - diagnostic imaging

Tuberculosis, Meningeal - drug therapy

Dura Mater - pathology

Humans

Middle Aged

Tuberculosis, Meningeal - pathology

Adult

Female

Male

Tuberculosis, Meningeal - diagnostic imaging

Antitubercular Agents - therapeutic use

Details

Title: Subtitle: Tuberculous cranial pachymeningitis
Creators: M J Thurtell - Department of Neurology, Royal Prince Alfred Hospital, NSW, Australia. matthewt@icn.usyd.edu.au
A B R Keed
M Yan
T Gottlieb
J M Spies
G M Halmagyi
Resource Type: Journal article
Publication Details: Neurology, Vol.68(4), pp.298-300
Publisher: United States
DOI: 10.1212/01.wnl.0000252367.99393.34
PMID: 17242338
ISSN: 0028-3878
eISSN: 1526-632X
Language: English
Date published: 01/23/2007
Academic Unit: Neurology; Ophthalmology and Visual Sciences
Record Identifier: 9983979987402771

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