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Tubingensin B, a cytotoxic carbazole alkaloid from the sclerotia of Aspergillus tubingensis
Journal article   Peer reviewed

Tubingensin B, a cytotoxic carbazole alkaloid from the sclerotia of Aspergillus tubingensis

Dale C Swenson, Mark R TePaske, Norman C Baenziger and James B Gloer
Acta crystallographica. Section C, Crystal structure communications, Vol.53(10), pp.1447-1449
1997
DOI: 10.1107/S0108270197003776

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Abstract

The crystal structure of tubingensin B, (1α,4α,4aα,7α,-14bβ)-(-)-2,3,4,4a,5,6,7,9- octahydro-4,4a-dimethyl-7-isopropyl-1H-7,14b-ethanobenzo[3,4]cyclohepta[1,2-b] carbazol-1-ol, C28H35NO, confirms the structure assigned from NMR spectra. The molecule forms hydrogen-bonded sheets parallel to the bc plane in the crystal. A disordered molecule of solvent, CHCl3, is included in the crystal.
Alcaloids Analytical, structural and metabolic biochemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology Heterocyclic compounds, pigments Other biological molecules

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