Journal article
Tumor Lysis Syndrome in a Retroperitoneal Sarcoma
JIM - high impact case reports, Vol.2(3), pp.2324709614542340-2324709614542340
2014
DOI: 10.1177/2324709614542340
PMCID: PMC4528897
PMID: 26425616
Abstract
In the present case, a 49-year-old white female presented to the clinic with a 2-month history of nausea, vomiting, and right upper quadrant pain. On examination a 3-cm mass on the right anterior scalene muscle was noted. A computed tomography scan was performed revealing a 8.7 × 7.7 × 6.1 cm retroperitoneal mass with possible invasion of the inferior vena cava and right renal and left common iliac veins. An excisional biopsy was performed with pathology compatible with spindle cell sarcoma. The patient was then sent for follow-up at the sarcoma clinic as an outpatient. However, before chemotherapy was to be started the patient would be admitted to the hospital with progressively worse nausea and vomiting. At that time the patient’s lab work showed lactic acidosis, acute renal failure, hyperuricemia, hyperphosphatemia, and hypocalcemia, which met the Cairo–Bishop criteria for tumor lysis syndrome (TLS). The patient was admitted to the intensive care unit and kidney dialysis initiated. The patient would become progressively obtunded at which time the family opted for hospice care. The patient eventually succumbed peacefully 3 days after her last admission. In this case report, we briefly review the literature on TLS in solid tumors, and we present a rare case of spontaneous TLS in a retroperitoneal sarcoma.
Details
- Title: Subtitle
- Tumor Lysis Syndrome in a Retroperitoneal Sarcoma
- Creators
- Yousef Zakharia - Georgia Regents University, Augusta, GA, USAJoshua Mansour - Georgia Regents University, Augusta, GA, USASrinivasa Vasireddi - Michigan State University, East Lansing, MI, USAKais Zakharia - Michigan State University, East Lansing, MI, USAEduard Fatakhov - Georgia Regents University, Augusta, GA, USAChristopher Koch - Georgia Regents University, Augusta, GA, USABorys Hrinczenko - Michigan State University, East Lansing, MI, USA
- Resource Type
- Journal article
- Publication Details
- JIM - high impact case reports, Vol.2(3), pp.2324709614542340-2324709614542340
- DOI
- 10.1177/2324709614542340
- PMID
- 26425616
- PMCID
- PMC4528897
- NLM abbreviation
- J Investig Med High Impact Case Rep
- ISSN
- 2324-7096
- eISSN
- 2324-7096
- Publisher
- SAGE Publications
- Language
- English
- Date published
- 2014
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984094326602771
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