Two Typical Glycosylated Metabolites of Tetrabromobisphenol A Formed in Plants: Excretion and Deglycosylation in Plant Root Zones

Xingwang Hou; Linfeng Wei; Yinyin Tang; Wenqian Kong; Jiyan Liu; Jerald L Schnoor; Guibin Jiang

doi:10.1021/acs.estlett.1c00084

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Two Typical Glycosylated Metabolites of Tetrabromobisphenol A Formed in Plants: Excretion and Deglycosylation in Plant Root Zones

Xingwang Hou, Linfeng Wei, Yinyin Tang, Wenqian Kong, Jiyan Liu, Jerald L Schnoor and Guibin Jiang

Environmental science & technology letters, Vol.8(4), pp.313-319

04/13/2021

DOI: 10.1021/acs.estlett.1c00084

PMCID: PMC8603600

PMID: 34805424

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https://www.ncbi.nlm.nih.gov/pmc/articles/8603600View

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Abstract

The glycosylation process was investigated for the common brominated flame retardant tetrabromobisphenol A (TBBPA) in hydroponic exposure systems with pumpkin seedlings. Two typical glycosylation metabolites of TBBPA formed in pumpkin seedlings, TBBPA mono-β-d-glucopyranoside (TBBPA MG) and TBBPA di-β-d-glucopyranoside (TBBPA DG), increasing their mass early in the exposure (reaching maximum masses of 608 ± 53 and 3806 ± 1570 pmol at 12 h, respectively) and then falling throughout exposure. These two metabolites were released from roots to rhizosphere solutions, where they also exhibited initial increases followed by decreasing trends (reaching maximum masses of 595 ± 272 pmol at 3 h and 77.1 ± 36.0 pmol at 6 h, respectively). However, a (pseudo)zero-order deglycosylation of TBBPA MG and TBBPA DG (during the first 1.5 h) back to TBBPA was unexpectedly detected in the hydroponic solutions containing pumpkin exudates and microorganisms. The function of microorganisms in the solutions was further investigated, revealing that the microorganisms were main contributors to deglycosylation. Plant detoxification through glycosylation and excretion, followed by deglycosylation of metabolites back to the toxic parent compound (TBBPA) in hydroponic solutions, provides new insight into the uptake, transformation, and environmental fate of TBBPA and its glycosylated metabolites in plant/microbial systems.

Contaminants in Aquatic and Terrestrial Environments

Details

Title: Subtitle: Two Typical Glycosylated Metabolites of Tetrabromobisphenol A Formed in Plants: Excretion and Deglycosylation in Plant Root Zones
Creators: Xingwang Hou - University of Chinese Academy of Sciences
Linfeng Wei - University of Chinese Academy of Sciences
Yinyin Tang - University of Chinese Academy of Sciences
Wenqian Kong - University of Chinese Academy of Sciences
Jiyan Liu - University of Chinese Academy of Sciences
Jerald L Schnoor - Department of Civil and Environmental Engineering
Guibin Jiang - University of Chinese Academy of Sciences
Resource Type: Journal article
Publication Details: Environmental science & technology letters, Vol.8(4), pp.313-319
DOI: 10.1021/acs.estlett.1c00084
PMID: 34805424
PMCID: PMC8603600
NLM abbreviation: Environ Sci Technol Lett
ISSN: 2328-8930
eISSN: 2328-8930
Publisher: American Chemical Society
Grant note: name: the National Key Research and Development Project, award: 2018YFC1800702; DOI: 10.13039/501100001809, name: the National Natural Science Foundation of China, award: 22006157
Language: English
Date published: 04/13/2021
Academic Unit: Civil and Environmental Engineering; Occupational and Environmental Health; Iowa Superfund Research Program
Record Identifier: 9984077373002771

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