Journal article
Two hydrolase resistant analogues of diadenosine 5',5"'-P1,P3-triphosphate for studies with Fhit, the human fragile histidine triad protein
Nucleosides & nucleotides, Vol.17(1-3), pp.301-308
01/1998
DOI: 10.1080/07328319808005178
PMCID: PMC2556045
PMID: 9708352
Abstract
The design and synthesis of analogues of diadenosine 5',5"'-P1,P3-triphosphate that are resistant to pyrophosphate hydrolysis is described in relation to their rôle in signalling and tumorigenesis involving the Fhit protein, the human fragile histidine triad protein, which is a novel Ap3A binding/cleaving protein.
Details
- Title: Subtitle
- Two hydrolase resistant analogues of diadenosine 5',5"'-P1,P3-triphosphate for studies with Fhit, the human fragile histidine triad protein
- Creators
- G Michael Blackburn - Department of Chemistry, Sheffield University, UK. g.m.blackburn@sheffield.ac.ukXiaohai Liu - University of SheffieldAngelika RöslerCharles Brenner
- Resource Type
- Journal article
- Publication Details
- Nucleosides & nucleotides, Vol.17(1-3), pp.301-308
- Publisher
- United States
- DOI
- 10.1080/07328319808005178
- PMID
- 9708352
- PMCID
- PMC2556045
- ISSN
- 0732-8311
- eISSN
- 2332-3892
- Grant note
- R01 CA075954-03 / NCI NIH HHS CA56336 / NCI NIH HHS R01 CA075954 / NCI NIH HHS CA75954 / NCI NIH HHS
- Language
- English
- Date published
- 01/1998
- Academic Unit
- Biochemistry and Molecular Biology; Internal Medicine
- Record Identifier
- 9983788597902771
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