Journal article
Type-2 diabetes mellitus: does prenatal care affect outcomes?
The journal of maternal-fetal & neonatal medicine, Vol.31(1), pp.93-97
01/02/2018
DOI: 10.1080/14767058.2016.1276558
PMID: 28076991
Abstract
Objective: To determine if prenatal care affects adverse perinatal outcomes in pregnant women with Type-2 diabetes mellitus (T2DM).
Study design: This was a retrospective cohort study of pregnant women with pregestational diabetes mellitus pregnancies in the state of California between 1997 and 2006, using vital statistics data linked to birth certificates. Women were stratified by time of presentation to care and we compared those who presented in the first trimester, third trimester, and those who had no prenatal care prior to delivery. Perinatal outcomes looked at included: preeclampsia, macrosomia, preterm delivery, cesarean delivery, and intrauterine fetal demise (IUFD). The two groups were compared with chi-squared testing to determine statistical significance.
Results: In women with pregestational diabetes those who presented at time of delivery had an 11.3% risk of IUFD compared to 0.9% in those who presented in the first trimester. There was also an increased rate of preterm birth in the late presentation cohort (29.4% at time of delivery versus 21.0% in the first trimester). After adjusting for possible confounding variables using logistic regression models, rates of IUFD and preterm delivery were still found to be statistically significant with adjusted odds ratios of 11.37 (95% CI: 6.10-21.16) and 1.55 (95% CI: 1.03-2.32), respectively. There were no differences in rates of macrosomia or preeclampsia between the three cohorts.
Conclusions: Treatment of T2DM throughout pregnancy leads to improved maternal and neonatal outcomes.
Details
- Title: Subtitle
- Type-2 diabetes mellitus: does prenatal care affect outcomes?
- Creators
- Allison J. Allen - Oregon Health & Science UniversityJonathan M. Snowden - Oregon Health & Science UniversityBernard Lau - Oregon Health & Science UniversityYvonne Cheng - California Pacific Medical CenterAaron B. Caughey - Oregon Health & Science University
- Resource Type
- Journal article
- Publication Details
- The journal of maternal-fetal & neonatal medicine, Vol.31(1), pp.93-97
- DOI
- 10.1080/14767058.2016.1276558
- PMID
- 28076991
- NLM abbreviation
- J Matern Fetal Neonatal Med
- ISSN
- 1476-7058
- eISSN
- 1476-4954
- Publisher
- Taylor & Francis
- Number of pages
- 5
- Grant note
- K99 / National Institute of Child Health and Human Development
- Language
- English
- Date published
- 01/02/2018
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9984848505302771
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