Journal article
Understanding Microbiome Effect on Immune Checkpoint Inhibition in Lung Cancer: Placing the Puzzle Pieces Together
Journal of immunotherapy (1997), Vol.41(8), pp.359-360
10/01/2018
DOI: 10.1097/CJI.0000000000000232
PMID: 29781826
Abstract
Over the past couple of years, human microbiome has received increasing attention as a regulator and predictor of response to the therapies of various diseases. It is speculated that manipulating gut microbiome can modify response to cancer immunotherapies as well. Through this review, we have critically analyzed our current understanding of gut microbiome as a modulator of immunotherapies in lung cancer, explained conflicting data, evaluated current gaps and extrapolated our present knowledge to generate directions for future investigations.
Details
- Title: Subtitle
- Understanding Microbiome Effect on Immune Checkpoint Inhibition in Lung Cancer: Placing the Puzzle Pieces Together
- Creators
- Umang Swami - University of IowaYousef Zakharia - University of Iowa Hospitals and ClinicsJun Zhang - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of immunotherapy (1997), Vol.41(8), pp.359-360
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1097/CJI.0000000000000232
- PMID
- 29781826
- ISSN
- 1524-9557
- eISSN
- 1537-4513
- Number of pages
- 2
- Grant note
- University of Iowa Start-up Funds IRG-15-176-40 / American Cancer Society P30CA086862 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Language
- English
- Date published
- 10/01/2018
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984548266302771
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