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Understanding and Improving Vaccine Effectiveness Estimates in the Age of Widespread Background Immunity: A Step Towards Improved Science Communication
Journal article   Open access   Peer reviewed

Understanding and Improving Vaccine Effectiveness Estimates in the Age of Widespread Background Immunity: A Step Towards Improved Science Communication

Edward Nirenberg and Eli N Perencevich
Clinical infectious diseases, Vol.76(9), pp.1535-1538
05/2023
DOI: 10.1093/cid/ciad124
PMID: 36883583
url
https://doi.org/10.1093/cid/ciad124View
Published (Version of record) Open Access

Abstract

Medical decision making and scientific communication around COVID-19 vaccines and booster doses requires proper understanding of how vaccine effectiveness estimates are determined and the potential biases inherent in current estimates. The importance of background immunity from prior infection is reviewed along with ideas for improving the vaccine effectiveness estimates.

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