Journal article
Unruptured Cerebral Aneurysms Do Not Shrink When They Rupture: Multicenter Collaborative Aneurysm Study Group
Neurosurgery, Vol.68(1), pp.155-161
01/01/2011
DOI: 10.1227/NEU.0b013e3181ff357c
PMID: 21150760
Abstract
Abstract BACKGROUND: The International Study of Intracranial Aneurysms found that for patients with no previous history of subarachnoid hemorrhage, small (< 7 mm) anterior circulation and posterior circulation aneurysms had a 0% and 2.5% risk of subarachnoid hemorrhage over 5 years, respectively. OBJECTIVE: To determine whether cerebral aneurysms shrink with rupture. METHODS: The clinical databases of 7 sites were screened for patients with imaging of cerebral aneurysms before and after rupture. Inclusion criteria included documented subarachnoid hemorrhage by imaging or lumbar puncture and intracranial imaging before and after cerebral aneurysm rupture. The patients were evaluated for aneurysm maximal height, maximal width, neck diameter, and other measurement parameters. Only a change of ≥ 2 mm was considered a true change. RESULTS: Data on 13 patients who met inclusion criteria were collected. The median age was 60, and 11 of the 13 patients (84.6%) were female. Only 5 patients had posterior circulation aneurysms. None of the aneurysms had a significant decrease in size. One aneurysm decreased by 1.8 mm in maximum size after rupture (7.7%). Six aneurysms had an increase in maximum size of at least 2 mm after rupture (46.2%) with a mean increase of 3.5 mm (± 0.5 mm). CONCLUSION: Unruptured aneurysms do not shrink when they rupture. The large percentage of ruptured small aneurysms in previous studies were likely small before they ruptured.
Details
- Title: Subtitle
- Unruptured Cerebral Aneurysms Do Not Shrink When They Rupture: Multicenter Collaborative Aneurysm Study Group
- Creators
- Maryam Rahman - Department of Neurosurgery, University of Florida, Gainesville, FloridaChristopher S Ogilvy - Department of Neurosurgery, Massachusetts General Hospital Boston, MassachusettsGregory J Zipfel - Department of Neurosurgery, Washington University, St Louis, MissouriColin P Derdeyn - Department of Neurosurgery, Washington University, St Louis, MissouriAdnan H Siddiqui - Department of Neurosurgery, University at Buffalo, Buffalo, New YorkKetan R Bulsara - Department of Neurosurgery, Yale University, New Haven, ConnecticutLouis J Kim - Department of Neurosurgery, University of Washington, Seattle, WashingtonHoward A Riina - Department of Neurosurgery, Weill Cornell Medical College, New York, New YorkJ Mocco - Department of Neurosurgery, University of Florida, Gainesville, FloridaBrian L Hoh - Department of Neurosurgery, University of Florida, Gainesville, Florida
- Resource Type
- Journal article
- Publication Details
- Neurosurgery, Vol.68(1), pp.155-161
- DOI
- 10.1227/NEU.0b013e3181ff357c
- PMID
- 21150760
- ISSN
- 0148-396X
- eISSN
- 1524-4040
- Language
- English
- Date published
- 01/01/2011
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020784402771
Metrics
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