Journal article
Unstable Childhood, Adult Adversity, and Smoking Accelerate Biological Aging Among Middle-Age African Americans: Similar Findings for GrimAge and PoAm
Journal of aging and health, Vol.34(4-5), pp.487-498
2022
DOI: 10.1177/08982643211043668
PMCID: PMC9851128
PMID: 34525884
Abstract
The recent biological clocks GrimAge and PoAm are robust predictors of morbidity and mortality. Little research, however, has investigated the factors that influence their ticking speed. No study has used multivariate analyses to examine whether childhood adversity, adult hardship, lifestyle practices, or some combination of these factors best explains acceleration of these indices.
Using a sample of 506 middle-age African Americans, the present study investigated the extent to which childhood instability, adult adversity, and lifestyle predict accelerated GrimAge and PoAm.
The two clocks were highly correlated and the pattern of findings was very similar for the two measures. Childhood instability, adult financial hardship, and smoking were significant predictors of both clocks.
The findings support a life course perspective where both the long arm of childhood as well as later life conditions influence speed of aging. Similar results across the two clocks enhance confidence in the findings.
Details
- Title: Subtitle
- Unstable Childhood, Adult Adversity, and Smoking Accelerate Biological Aging Among Middle-Age African Americans: Similar Findings for GrimAge and PoAm
- Creators
- Ronald L Simons - University of GeorgiaMei Ling Ong - University of Georgia, Athens, GA, USA;;Man-Kit Lei - University of Georgia, Athens, GA, USA;;Eric Klopack - University of Southern CaliforniaMark Berg - University of IowaYue Zhang - University of GeorgiaRobert Philibert - University of IowaSteven S R Beach - University of Georgia, Athens, GA, USA;;
- Resource Type
- Journal article
- Publication Details
- Journal of aging and health, Vol.34(4-5), pp.487-498
- DOI
- 10.1177/08982643211043668
- PMID
- 34525884
- PMCID
- PMC9851128
- NLM abbreviation
- J Aging Health
- ISSN
- 0898-2643
- eISSN
- 1552-6887
- Grant note
- R01 CA220254 / NCI NIH HHS
- Language
- English
- Electronic publication date
- 09/15/2021
- Date published
- 2022
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Psychiatry; Sociology and Criminology; Iowa Neuroscience Institute; Center for Social Science Innovation; Injury Prevention Research Center; Public Policy Center (Archive)
- Record Identifier
- 9984282619802771
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