Journal article
Updates on Management for Acute and Chronic Phenotypes of Neonatal Pulmonary Hypertension
Clinics in perinatology, Vol.47(3), pp.593-615
09/2020
DOI: 10.1016/j.clp.2020.05.006
PMID: 32713453
Abstract
Neonatal pulmonary hypertension is a heterogeneous disease in term and preterm neonates. It is characterized by persistent increase of pulmonary artery pressures after birth (acute) or an increase in pulmonary artery pressures after approximately 4 weeks of age (chronic); both phenotypes result in exposure of the right ventricle to sustained high afterload. In-depth clinical assessment plus echocardiographic measures evaluating pulmonary blood flow, pulmonary vascular resistance, pulmonary capillary wedge pressure, and myocardial contractility are needed to determine the cause and provide individualized targeted therapies. This article summarizes the causes, risk factors, hemodynamic assessment, and management of neonatal pulmonary hypertension.
Details
- Title: Subtitle
- Updates on Management for Acute and Chronic Phenotypes of Neonatal Pulmonary Hypertension
- Creators
- Jessica Lauren Ruoss - Division of Neonatology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USADanielle R. Rios - University of IowaPhilip T. Levy - Boston Children's Hospital
- Resource Type
- Journal article
- Publication Details
- Clinics in perinatology, Vol.47(3), pp.593-615
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.clp.2020.05.006
- PMID
- 32713453
- ISSN
- 0095-5108
- eISSN
- 1557-9840
- Language
- English
- Date published
- 09/2020
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984353948302771
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