Uptake of Adenosine by Cultured Cerebral Vascular Smooth Muscle Cells

David W Beck; Harry V Vinters; Steven A Moore; Michael N Hart; Pasquale A Cancilla

doi:10.1111/j.1471-4159.1983.tb09037.x

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Uptake of Adenosine by Cultured Cerebral Vascular Smooth Muscle Cells

Journal article

Peer reviewed

Uptake of Adenosine by Cultured Cerebral Vascular Smooth Muscle Cells

David W Beck, Harry V Vinters, Steven A Moore, Michael N Hart and Pasquale A Cancilla

Journal of neurochemistry, Vol.41(4), pp.939-941

04/1983

DOI: 10.1111/j.1471-4159.1983.tb09037.x

PMID: 6619860

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Abstract

: Adenosine uptake by cerebral smooth muscle cells is a carrier‐mediated process. The Km value for adenosine uptake is 10.0 μM and the Vmax is 0.95 nmol/ min‐mg cell protein. This uptake system is inhibited by the adenosine analog 2‐chloroadenosine at low adenosine concentrations. These results prove the existence of a nucleoside transport system associated with cerebral smooth muscle.

Cerebral smooth muscle

Adenosine

Kinetics

Uptake

Details

Title: Subtitle: Uptake of Adenosine by Cultured Cerebral Vascular Smooth Muscle Cells
Creators: David W Beck
Harry V Vinters
Steven A Moore
Michael N Hart
Pasquale A Cancilla
Resource Type: Journal article
Publication Details: Journal of neurochemistry, Vol.41(4), pp.939-941
Publisher: Blackwell Publishing Ltd; Oxford, UK
DOI: 10.1111/j.1471-4159.1983.tb09037.x
PMID: 6619860
ISSN: 0022-3042
eISSN: 1471-4159
Number of pages: 3
Language: English
Date published: 04/1983
Academic Unit: Pathology
Record Identifier: 9984046805502771

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