Journal article
Urceolatin, a Structurally Unique Bromophenol from Polysiphonia urceolata
Organic letters, Vol.10(7), pp.1429-1432
04/01/2008
DOI: 10.1021/ol800230t
PMID: 18324823
Abstract
(Chemical Equation Presented) 6-Bromo-1-(3-bromo-4,5-dihydroxybenzyl) phenanthro[4,5-bcd]furan-2,3,5-triol (urceolatin, 1), a highly oxygenated bromophenol containing an unprecedented naturally occurring benzylphenanthro[4, 5-bcd]furan unit, was isolated from the marine red alga Polysiphonia urceolata. Its structure was established on the basis of extensive spectroscopic analysis. Compound 1 displayed significant DPPH radical-scavenging activity with an IC50 value of 7.9 μM, which is 10-fold more potent than that of the positive control, butylated hydroxytoluene. © 2008 American Chemical Society.
Details
- Title: Subtitle
- Urceolatin, a Structurally Unique Bromophenol from Polysiphonia urceolata
- Creators
- Ke Li - Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, P. R. China, Graduate School of Chinese Academy of Sciences, Beijing 100049, P. R. China, and Department of Chemistry, University of Iowa, Iowa City, Iowa 52242Xiao-Ming Li - Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, P. R. China, Graduate School of Chinese Academy of Sciences, Beijing 100049, P. R. China, and Department of Chemistry, University of Iowa, Iowa City, Iowa 52242Nai-Yun Ji - Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, P. R. China, Graduate School of Chinese Academy of Sciences, Beijing 100049, P. R. China, and Department of Chemistry, University of Iowa, Iowa City, Iowa 52242James B Gloer - Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, P. R. China, Graduate School of Chinese Academy of Sciences, Beijing 100049, P. R. China, and Department of Chemistry, University of Iowa, Iowa City, Iowa 52242Bin-Gui Wang - Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, P. R. China, Graduate School of Chinese Academy of Sciences, Beijing 100049, P. R. China, and Department of Chemistry, University of Iowa, Iowa City, Iowa 52242
- Resource Type
- Journal article
- Publication Details
- Organic letters, Vol.10(7), pp.1429-1432
- DOI
- 10.1021/ol800230t
- PMID
- 18324823
- ISSN
- 1523-7060
- eISSN
- 1523-7052
- Language
- English
- Date published
- 04/01/2008
- Academic Unit
- Chemistry
- Record Identifier
- 9984216713302771
Metrics
4 Record Views