Journal article
Urinary and Sexual Function after Perineal Urethrostomy for Urethral Stricture Disease: An Analysis from the TURNS
The Journal of urology, Vol.201(5), pp.956-961
01/28/2019
DOI: 10.1097/JU.0000000000000027
PMID: 30676476
Abstract
Perineal urethrostomy is a viable option for many complex urethral strictures. However, to our knowledge no comparison with anterior urethroplasty regarding patient reported outcome measures has been published. We compared these groups using a large multi-institution database.
We performed a retrospective study of anterior urethroplasty in the TURNS (Trauma and Urologic Reconstruction Network of Surgeons) database. The anterior urethroplasty cohort was defined by long strictures greater than 6 cm. We compared demographic, clinical, urinary and sexual characteristics using validated patient reported outcome measures between patients treated with long stricture anterior urethroplasty and those who underwent perineal urethrostomy.
Of the 131 patients 92 treated with long stricture anterior urethroplasty and 39 treated with perineal urethrostomy met study inclusion criteria. The cumulative incidence of failure at 2 years was 30.2% (95% CI 18.3-47.3) for long stricture anterior urethroplasty and 14.5% (95% CI 4.8-39.1) for perineal urethrostomy (p = 0.09). Compared to baseline metrics, patients who underwent long stricture anterior urethroplasty and perineal urethrostomy had similar improvements in urinary function and stable sexual function after surgery.
Patients reported improvement in urinary function after perineal urethrostomy with no deleterious effect on sexual function. These patient reported outcome measures were comparable to those of long stricture anterior urethroplasty. Perineal urethrostomy failure rates were similar to those of long stricture anterior urethroplasty.
Details
- Title: Subtitle
- Urinary and Sexual Function after Perineal Urethrostomy for Urethral Stricture Disease: An Analysis from the TURNS
- Creators
- Gregory P Murphy - Division of Urology, Washington University, St. Louis, MissouriKirkpatrick B Fergus - Departments of Urology, University of California-San Francisco, San FranciscoThomas W Gaither - Departments of Urology, University of California-San Francisco, San FranciscoNima Baradaran - Departments of Urology, University of California-San Francisco, San FranciscoBryan B Voelzke - University of Washington, Seattle, WashingtonJeremy B Myers - University of Utah, Salt Lake City, UtahBradley A Erickson - University of Iowa, Iowa City, IowaSean P Elliott - University of Minnesota, Minneapolis, MinnesotaNejd F Alsikafi - UroPartners, Gurnee, IllinoisAlex J Vanni - Lahey Hospital and Medical Center, Burlington, MassachusettsJill C Buckley - University of California-San Diego Health System, San Diego, CaliforniaBenjamin N Breyer - Departments of Urology, University of California-San Francisco, San Francisco
- Resource Type
- Journal article
- Publication Details
- The Journal of urology, Vol.201(5), pp.956-961
- DOI
- 10.1097/JU.0000000000000027
- PMID
- 30676476
- NLM abbreviation
- J Urol
- ISSN
- 0022-5347
- eISSN
- 1527-3792
- Publisher
- United States
- Language
- English
- Date published
- 01/28/2019
- Academic Unit
- Urology
- Record Identifier
- 9984051596702771
Metrics
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