Journal article
Urticaria pigmentosa responsive to nifedipine
Journal of the American Academy of Dermatology, Vol.11(4), pp.740-743
1984
DOI: 10.1016/S0190-9622(84)70233-7
PMID: 6491000
Abstract
A patient with symptomatic urticaria pigmentosa who responded to nifedipine therapy is reported. Relief from cold-induced urtication and flushing was obtained with 10 mg taken orally three times daily. Calcium influx is an early step in the degranulation of mast cells. We hypothesize that the beneficial effect of nifedipine was due to calcium-channel blockade causing elevation of the mast cell threshold for degranulation.
Details
- Title: Subtitle
- Urticaria pigmentosa responsive to nifedipine
- Creators
- Janet A FairleyAlice P PentlandJohn J Voorhees
- Resource Type
- Journal article
- Publication Details
- Journal of the American Academy of Dermatology, Vol.11(4), pp.740-743
- DOI
- 10.1016/S0190-9622(84)70233-7
- PMID
- 6491000
- NLM abbreviation
- J Am Acad Dermatol
- ISSN
- 0190-9622
- eISSN
- 1097-6787
- Publisher
- Mosby, Inc
- Language
- English
- Date published
- 1984
- Academic Unit
- Dermatology
- Record Identifier
- 9984025682802771
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