Journal article
Use of Aminocaproic Acid in Combination With Extracorporeal Membrane Oxygenation in a Case of Leptospirosis Pulmonary Hemorrhage Syndrome
Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, Vol.11(11), p.1179548416686068
03/02/2017
DOI: 10.1177/1179548416686068
PMCID: PMC5392109
PMID: 28469503
Abstract
A 32-year-old man presented with a 10-day history of fever, chills, nausea, vomiting, myalgia, nonproductive cough, and worsening dyspnea after freshwater swimming in the Caribbean 1 week prior to presentation. Shortly after arrival at the hospital, the patient developed severe respiratory distress with massive hemoptysis. Based on serologic workup, he was diagnosed with leptospirosis pulmonary hemorrhage syndrome leading to diffuse alveolar hemorrhage, severe hypoxemic respiratory failure, and multiorgan failure. He received appropriate antibiotic coverage along with hemodynamic support with norepinephrine and vasopressin, mechanical ventilation, and renal replacement therapy in an intensive care unit. Introduction of extracorporeal membrane oxygenation was initiated to provide lung-protective ventilation supporting the recovery of his pulmonary function. Aminocaproic acid was used to stop and prevent further alveolar hemorrhage. He fully recovered thereafter; however, it is uncertain whether it was the use of aminocaproic acid that led to the resolution of his disease.
Details
- Title: Subtitle
- Use of Aminocaproic Acid in Combination With Extracorporeal Membrane Oxygenation in a Case of Leptospirosis Pulmonary Hemorrhage Syndrome
- Creators
- Miguel Pardinas - Division of Internal Medicine, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USARodrigo Mendirichaga - Division of Internal Medicine, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USAGaurav Budhrani - Division of Anesthesiology, Emory University, Atlanta, GA, USARajan Garg - Division of Pulmonary, Critical Care and Sleep Medicine, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USALuis Rosario - Division of Pulmonary, Critical Care and Sleep Medicine, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USARene Rico - Division of Pulmonary, Critical Care and Sleep Medicine, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USAAnthony Panos - Division of Thoracic Transplantation and Cardiothoracic Surgery, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USAHorst Baier - Division of Pulmonary, Critical Care and Sleep Medicine, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USAStefanie Krick - Division of Pulmonary, Critical Care and Sleep Medicine, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, FL, USA
- Resource Type
- Journal article
- Publication Details
- Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, Vol.11(11), p.1179548416686068
- DOI
- 10.1177/1179548416686068
- PMID
- 28469503
- PMCID
- PMC5392109
- NLM abbreviation
- Clin Med Insights Circ Respir Pulm Med
- ISSN
- 1179-5484
- eISSN
- 1179-5484
- Publisher
- SAGE Publications; Sage UK: London, England
- Language
- English
- Date published
- 03/02/2017
- Academic Unit
- Surgery; Cardiothoracic Surgery
- Record Identifier
- 9984051730902771
Metrics
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