Journal article
Use of Cobalt–Chromium 64 Wires Surpass Evolve for the Treatment of Remnant Intracranial Aneurysms: A Subanalysis From the SEASE International Registry
Stroke: vascular and interventional neurology, Vol.5(2), e001470
03/2025
DOI: 10.1161/SVIN.124.001470
PMCID: PMC12671630
PMID: 41573176
Appears in UI Libraries Support Open Access
Abstract
BACKGROUND
The use of the Surpass Evolve flow diverter for intracranial aneurysms (IAs) has shown promising results, but there are no studies that evaluated its effectiveness for remnant previously treated IAs. This study aimed to evaluate the safety and effectiveness of Surpass Evolve for previously treated IAs.
METHODS
This subanalysis is derived from the SEASE (Safety and Effectiveness Assessment of Surpass Evolve) registry, a retrospective, multicentric, international cohort conducted across 15 academic institutions in North America and Europe between July 2020 and October 2022. Adult patients undergoing Surpass Evolve implantation for single saccular IAs were grouped into those with previously treated IAs by coiling or intrasaccular‐devices and those with untreated IAs. Baseline characteristics and outcomes were compared.
RESULTS
This study included 257 patients with IAs. Of those, 66 patients had previously treated IAs (median time between diagnosis and initial treatment and retreatment: 6.28 months), and 191 patients had untreated IAs. Of the 246 patients with 10.5 months of imaging follow‐up, the core lab adjudicated complete occlusion was less in previously treated IAs compared with untreated IAs (59.7% versus 72.3%; adjusted odds ratio, 0.43 [95% CI, 0.21–0.88]; P = 0.022). Furthermore, we found similar rates of adequate occlusion between previously treated IAs (83.9%) and untreated IAs (82.1%, P = 0.746). There was no difference in rates of major stroke (1.5% versus 2.6%, P>0.999), mortality (1.5% versus 1.0%, P>0.999), modified Rankin Scale score 0–2 (93.7% versus 95.7%, P = 0.504), and retreatment (1.6% versus 3.3%, P = 0.684) between the 2 groups.
CONCLUSION
Our results revealed reasonable rates of occlusion and an acceptable safety profile for the use of Surpass Evolve to treat previously treated IAs. Future prospective studies with longer follow‐ups are warranted to explore the findings further.
Details
- Title: Subtitle
- Use of Cobalt–Chromium 64 Wires Surpass Evolve for the Treatment of Remnant Intracranial Aneurysms: A Subanalysis From the SEASE International Registry
- Creators
- Mahmoud Dibas - University of IowaJuan Vivanco-Suarez - University of IowaDemetrius Klee Lopes - The Spine InstituteRicardo A. Hanel - Baptist Medical Center JacksonvilleAaron Rodriguez-Calienes - Department of Neurology University of Iowa Hospitals and Clinics Iowa City IAGustavo M. Cortez - Baptist Medical Center JacksonvilleJohanna T. Fifi - Mount Sinai Health SystemAlex Devarajan - Mount Sinai Health SystemGabor Toth - Cleveland ClinicThomas E. Patterson - Cleveland ClinicDavid Altschul - Montefiore Medical CenterVitor M. Pereira - St. Michael's HospitalXiao Yu Eileen Liu - St. Michael's HospitalAjit S. Puri - University of Massachusetts Chan Medical SchoolAnna L. Kühn - University of Massachusetts Chan Medical SchoolWaldo R. Guerrero - University of South FloridaPriyank Khandelwal - Robert Wood Johnson University HospitalIvo Bach - Robert Wood Johnson University HospitalPeter T. Kan - The University of Texas Medical Branch at GalvestonGautam Edhayan - The University of Texas Medical Branch at GalvestonMario Martinez-Galdamez - Hospital Clínico Universitario de ValladolidCurtis Given - Central Baptist HospitalBradley A. Gross - University of PittsburghSandra Narayanan - Pacific Heart InstituteMilagros Galecio-Castillo - University of IowaShahram Derakhshani - Queen's HospitalSantiago Ortega-Gutierrez - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Stroke: vascular and interventional neurology, Vol.5(2), e001470
- DOI
- 10.1161/SVIN.124.001470
- PMID
- 41573176
- PMCID
- PMC12671630
- NLM abbreviation
- Stroke Vasc Interv Neurol
- ISSN
- 2694-5746
- eISSN
- 2694-5746
- Publisher
- Wiley
- Grant note
- Stryker Neurovascular
Stryker Neurovascular funded this study through an investigator-initiated grant. The funding source was not involved in study design, monitoring, data collection, statistical analyses, interpretation of results, or manuscript writing.
- Language
- English
- Electronic publication date
- 01/04/2025
- Date published
- 03/2025
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984771664602771
Metrics
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