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Use of Computerized Psychomotor Testing in Determining CNS Effects of Drugs
Journal article   Peer reviewed

Use of Computerized Psychomotor Testing in Determining CNS Effects of Drugs

Richard Berchou and Robert I Block
Perceptual and motor skills, Vol.57(3), pp.691-700
12/1983
DOI: 10.2466/pms.1983.57.3.691
PMID: 6664751

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Abstract

wo interactive, computer-controlled tests--critical flicker fusion and discriminant reaction time tasks--are described. These tasks, and subjective sedation ratings using visual analogue scales, were shown to be sensitive in a dose-related fashion to the effects of CNS depressants (diazepam, 15 mg and lorazepam, 1 and 2 mg). Such brief, interactive, computerized tasks should be useful in screening new agents for CNS activity in humans.

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