Use of a computer-controlled motion phantom to investigate the temporal and spatial fidelity of HYPR processing

Lauren Keith; Mahdi Rahimi; James Holmes; Jean Brittain; Frank Korosec

doi:10.1002/mrm.24707

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Use of a computer-controlled motion phantom to investigate the temporal and spatial fidelity of HYPR processing

Journal article

Open access

Peer reviewed

Use of a computer-controlled motion phantom to investigate the temporal and spatial fidelity of HYPR processing

Lauren Keith, Mahdi Rahimi, James Holmes, Jean Brittain and Frank Korosec

Magnetic resonance in medicine, Vol.71(2), pp.702-710

02/2014

DOI: 10.1002/mrm.24707

PMCID: PMC4107196

PMID: 23475821

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https://doi.org/10.1002/mrm.24707View

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Abstract

In this work, we investigate the spatial and temporal fidelity of highly constrained backPRojection (HYPR) processing using a computer-controlled motion phantom. The goal of this experimental set-up was to provide not only well-defined temporal dynamics and spatial characteristics of the motion phantom, but also circumstances that imitate in vivo scenarios. The phantom was designed to represent an artery flanked on both sides by vein. Both arterial and venous components have different temporal dynamics but are confluent, which corresponds to a difficult scenario for HYPR. Spatial and temporal fidelity was investigated by measuring signal intensity profiles through the phantom both orthogonal to as well as along the direction of motion. Spatial fidelity profiles measured from the HYPR processed images yielded full-width-at-half-maximum values very similar to those measured in non-HYPR-processed images. Furthermore, there was no significant spreading of the motion phantom leading edge in HYPR processed images. Although HYPR processing has certain characteristic artifacts that are discussed, the technique can be used to improve image quality of highly undersampled time frame images with minimal loss of spatial or temporal fidelity.

Artifacts

Blood Vessels - anatomy & histology

Equipment Design

Equipment Failure Analysis

Image Enhancement - methods

Image Interpretation, Computer-Assisted - instrumentation

Image Interpretation, Computer-Assisted - methods

Magnetic Resonance Angiography - instrumentation

Magnetic Resonance Angiography - methods

Motion

Phantoms, Imaging

Reproducibility of Results

Robotics - instrumentation

Sensitivity and Specificity

Spatio-Temporal Analysis

Details

Title: Subtitle: Use of a computer-controlled motion phantom to investigate the temporal and spatial fidelity of HYPR processing
Creators: Lauren Keith - University of Wisconsin–Madison
Mahdi Rahimi - University of Wisconsin–Madison
James Holmes - MR Global Applied Science Laboratory Madison Wisconsin USA
Jean Brittain - MR Global Applied Science Laboratory Madison Wisconsin USA
Frank Korosec - University of Wisconsin–Madison
Resource Type: Journal article
Publication Details: Magnetic resonance in medicine, Vol.71(2), pp.702-710
DOI: 10.1002/mrm.24707
PMID: 23475821
PMCID: PMC4107196
ISSN: 0740-3194
eISSN: 1522-2594
Grant note: R01 EB006882 / NIBIB NIH HHS
Language: English
Date published: 02/2014
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology
Record Identifier: 9984295026302771

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