Use of a new method in reaching consensus on the cause of cytologic-histologic correlation discrepancy

Stephen S RAAB; Chad H STONE; Eva M WOJCIK; Kim R GEISINGER; Laila DAHMOUSH; Fernando U GARCIA; Dana Marie GRZYBICKI; Janine E JANOSKY; Frederick A MEIER; Richard J ZARBO

doi:10.1309/1790-JN2Y-WCG8-33VU

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Use of a new method in reaching consensus on the cause of cytologic-histologic correlation discrepancy

Journal article

Open access

Peer reviewed

Use of a new method in reaching consensus on the cause of cytologic-histologic correlation discrepancy

Stephen S RAAB, Chad H STONE, Eva M WOJCIK, Kim R GEISINGER, Laila DAHMOUSH, Fernando U GARCIA, Dana Marie GRZYBICKI, Janine E JANOSKY, Frederick A MEIER and Richard J ZARBO

American journal of clinical pathology, Vol.126(6), pp.836-842

2006

DOI: 10.1309/1790-JN2Y-WCG8-33VU

PMID: 17074685

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https://doi.org/10.1309/1790-JN2Y-WCG8-33VUView

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Abstract

Pathologists exhibit very poor agreement in adjudicating the cause of cytologic-histologic correlation discrepancies, which contributes to problems in designing interventions to reduce discrepancy frequency. In this observational study, we developed a visual method of adjudicating discrepancy cause, termed the No-Blame Box method, which consisted of initially assessing specimen interpretability by separately evaluating specimen quality and the presence of tumor. Five pathologists blindly adjudicated the cause of discrepancy in pulmonary specimens from 40 patients. The kappa statistic of all pathologist pairs in adjudicating discrepancy cause using the No-Blame Box method ranged from 0.400 to 0.796, indicating acceptable to excellent agreement. Pathologists ranged in their assessment of specimen interpretability from 13% to 20%, and in no case did all 5 pathologists concur that a specimen was interpretable. Most discrepancies resulted from pathologists diagnosing noninterpretable samples. Pathologists who used the No-Blame Box showed significant agreement in the adjudication of discrepancy cause.

Biological and medical sciences

Investigative techniques, diagnostic techniques (general aspects)

Medical sciences

Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques

Details

Title: Subtitle: Use of a new method in reaching consensus on the cause of cytologic-histologic correlation discrepancy
Creators: Stephen S RAAB - Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Chad H STONE - Department of Pathology, Henry Ford Health System, Detroit, MI, United States
Eva M WOJCIK - Department of Pathology, Loyola University Medical Center, Maywood, IL, United States
Kim R GEISINGER - Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC, United States
Laila DAHMOUSH - Department of Pathology, University of Iowa Healthcare, Iowa City, IA, United States
Fernando U GARCIA - Department of Pathology, Drexel University College of Medicine, Philadelphia, PA, United States
Dana Marie GRZYBICKI - Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Janine E JANOSKY - Department of Family Medicine and Clinical Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Frederick A MEIER - Department of Pathology, Henry Ford Health System, Detroit, MI, United States
Richard J ZARBO - Department of Pathology, Henry Ford Health System, Detroit, MI, United States
Resource Type: Journal article
Publication Details: American journal of clinical pathology, Vol.126(6), pp.836-842
Publisher: American Society of Clinical Pathologists; Chicago, IL
DOI: 10.1309/1790-JN2Y-WCG8-33VU
PMID: 17074685
ISSN: 0002-9173
eISSN: 1943-7722
Language: English
Date published: 2006
Academic Unit: Pathology; Urology
Record Identifier: 9984046922802771

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