Journal article
Use of alcohols as cosolvents in enzyme-facilitated transport of organic acids through a liquid membrane
Journal of membrane science, Vol.95(1), pp.83-91
1994
DOI: 10.1016/0376-7388(94)85031-3
Abstract
Further applications and developments were studied for the use of enzyme-facilitated liquid membranes (EFLM). The use of ethanol as a cosolvent in the aqueous phase of the EFLM enhanced the facilitated transport of phenyl-acetic acid by more than 13 times relative to the case where water with low butanol concentrations was used, and more than 1000-fold relative to non-facilitated transport in the butanol/water system. This transport enhancement is proposed to result from a favorable shift in the equilibrium between phenylacetic acid and its ester (ethyl phenylacetate) which is the species transported across the liquid membrane. The enhancement goes through a maximum with increasing ethanol content that is proposed to result from the observed denaturing of the enzyme at high ethanol concentrations. A simple model is proposed which qualitatively describes the observed enhancement by ethanol blends.
Details
- Title: Subtitle
- Use of alcohols as cosolvents in enzyme-facilitated transport of organic acids through a liquid membrane
- Creators
- David G RethwischSanghamitra ParidaGao YiJonathan S Dordick
- Resource Type
- Journal article
- Publication Details
- Journal of membrane science, Vol.95(1), pp.83-91
- Publisher
- Elsevier B.V
- DOI
- 10.1016/0376-7388(94)85031-3
- ISSN
- 0376-7388
- eISSN
- 1873-3123
- Language
- English
- Date published
- 1994
- Academic Unit
- Chemical and Biochemical Engineering
- Record Identifier
- 9984003924602771
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