Journal article
Use of extracorporeal membrane oxygenation in neonates with congenital anomalies of the kidney and urinary tract: a multicenter survey of current practices across CHNC and Pedi-ECMO centers
Pediatric nephrology (Berlin, West)
05/02/2026
DOI: 10.1007/s00467-026-07301-x
PMID: 42069982
Abstract
This study aimed to characterize practices and decision-making for extracorporeal membrane oxygenation (ECMO) for congenital anomalies of the kidney and urinary tract (CAKUT).
General practices (GP) section inquired about institutional practices and barriers, ECMO criteria, and dialysis. The hypothetical cases (HC) illustrated four clinical scenarios with varying degrees of renal severity for ECMO candidacy.
Then, 99 (42 centers) and 91 (38 centers) physicians completed the GP and HC components, respectively. The majority considered ECMO on a case-by-case basis (66%). Bilateral renal agenesis was the most common diagnosis for exclusion (52%). Prenatal markers used for ECMO exclusion included anhydramnios (43%) and lung volumes (43%). The majority of centers had nephrology involved in ECMO decision-making. Challenges for implementing ECMO included disease heterogeneity (79%) and poor evidence on outcomes (66%). HC responses demonstrated variability in considering ECMO for CAKUT.
Variability among providers and institutes underscores the need for consensus-based guidelines to optimize decision-making and outcomes.
Details
- Title: Subtitle
- Use of extracorporeal membrane oxygenation in neonates with congenital anomalies of the kidney and urinary tract: a multicenter survey of current practices across CHNC and Pedi-ECMO centers
- Creators
- Syed Ahmed - Southwestern Medical CenterBurhan Mahmood - Children's Hospital of PittsburghJohn Daniel - Children's Mercy HospitalSandy Johng - Seattle Children's HospitalAmy Strong - University of IowaJohn Ibrahim - The University of Texas Southwestern Medical CenterJune Hu - The University of Texas Southwestern Medical CenterKara Short - Children's of AlabamaKelsey Montgomery - Riley Hospital for ChildrenKeri Drake - The University of Texas Southwestern Medical CenterKushal Bhakta - Children's Hospital of Orange CountyLeslie Lusk - UCSF Benioff Children's HospitalMary Revenis - Children's NationalPratibha Thakkar - Children's Hospital of OklahomaRuth Seabrook - Primary Children's HospitalSamir Pandya - The University of Texas Southwestern Medical CenterSarah Keene - Children's Healthcare of AtlantaSharada Gowda - Texas Children's HospitalSuma Hoffman - Children's NationalTahagod Mohamed - Nationwide Children's HospitalTara Beck - Children's Hospital of PittsburghTasnim Najaf - St. Louis Children's HospitalRobert DiGeronimo - Seattle Children's HospitalNatalie Rintoul - Children's Hospital of PhiladelphiaAbhishek Makkar - The University of Texas Southwestern Medical Center
- Resource Type
- Journal article
- Publication Details
- Pediatric nephrology (Berlin, West)
- DOI
- 10.1007/s00467-026-07301-x
- PMID
- 42069982
- NLM abbreviation
- Pediatr Nephrol
- ISSN
- 1432-198X
- eISSN
- 1432-198X
- Publisher
- Springer Nature
- Language
- English
- Electronic publication date
- 05/02/2026
- Academic Unit
- Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics
- Record Identifier
- 9985159231202771
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