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Use of phosphazene base and phase-transfer conditions for regiospecific alkylative isomerization of vinyl sulfones capable of undergoing β-elimination reactions
Journal article   Peer reviewed

Use of phosphazene base and phase-transfer conditions for regiospecific alkylative isomerization of vinyl sulfones capable of undergoing β-elimination reactions

Zhendong Jin and P.L. Fuchs
Tetrahedron letters, Vol.37(30), pp.5249-5252
1996
DOI: 10.1016/0040-4039(96)01111-2

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Abstract

Using phosphazene base, P 4-t-Bu or basic phase-transfer catalyst conditions, vinyl sulfones were regiospecifically alkylated at the α-position. No β-elimination products were observed in a system capable of undergoing anion-promoted β-elimination. The scope and limitations of these reactions were studied. Graphic

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