Use of platelet concentrates in oral surgery of patients with osteonecrosis: a scoping review

Carlos Eduardo Dutra Rufato; Mayara Colpo Prado; Renan Luiz Luft; Dionatan Zauza; Yara T C Silva-Sousa; Mateus Bertolini Fernandes Dos Santos; Rafael Sarkis-Onofre

doi:10.1590/0103-6440202305254

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Use of platelet concentrates in oral surgery of patients with osteonecrosis: a scoping review

Journal article

Open access

Peer reviewed

Use of platelet concentrates in oral surgery of patients with osteonecrosis: a scoping review

Carlos Eduardo Dutra Rufato, Mayara Colpo Prado, Renan Luiz Luft, Dionatan Zauza, Yara T C Silva-Sousa, Mateus Bertolini Fernandes Dos Santos and Rafael Sarkis-Onofre

Brazilian dental journal, Vol.34(2), pp.1-13

03/01/2023

DOI: 10.1590/0103-6440202305254

PMCID: PMC10208296

PMID: 37194847

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https://doi.org/10.1590/0103-6440202305254View

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Abstract

The objective of this study was to map, through a scoping review, the evidence available in the literature on the use of platelet concentrates in compromised patients undergoing oral surgeries. Searches were performed in electronic databases for clinical studies with compromised patients undergoing oral surgery who used platelet concentrates. Only studies published in English were included. Two independent researchers carried out the selection of studies. The study design and objective, surgical procedure and platelet concentrate used, systemic involvement, analyzed outcome, and main results were extracted. A descriptive analysis of the data was performed. Twenty-two studies met the eligibility criteria and were included. Case series was the most frequent study design among the included studies (41.0%). In terms of systemic disability, 19 studies reported patients with cancer and related to surgical treatment 16 studies reported patients underwent treatment for osteonecrosis related to the use of the drug. The most used platelet concentrate was pure platelet-rich fibrin (P-PRF). In general, most studies recommend the use of platelet concentrates. Thus, the results of this study suggest that the evidence related to the use of platelet concentrates in compromised patients when undergoing oral surgeries is still initial. Also, most studies assessed the use of platelet concentrates in patients with osteonecrosis.

Bisphosphonate-Associated Osteonecrosis of the Jaw

Humans

Oral Surgical Procedures

Surgery, Oral - methods

Details

Title: Subtitle: Use of platelet concentrates in oral surgery of patients with osteonecrosis: a scoping review
Creators: Carlos Eduardo Dutra Rufato - Graduate Program in Dentistry, Atitus Education, Passo Fundo, RS, Brazil
Mayara Colpo Prado - Graduate Program in Dentistry, Atitus Education, Passo Fundo, RS, Brazil
Renan Luiz Luft - Universidade de Ribeirão Preto
Dionatan Zauza - Graduate Program in Dentistry, Atitus Education, Passo Fundo, RS, Brazil
Yara T C Silva-Sousa - Universidade de Ribeirão Preto
Mateus Bertolini Fernandes Dos Santos - Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil
Rafael Sarkis-Onofre - Graduate Program in Dentistry, Atitus Education, Passo Fundo, RS, Brazil
Resource Type: Journal article
Publication Details: Brazilian dental journal, Vol.34(2), pp.1-13
DOI: 10.1590/0103-6440202305254
PMID: 37194847
PMCID: PMC10208296
NLM abbreviation: Braz Dent J
ISSN: 0103-6440
eISSN: 1806-4760
Language: English
Date published: 03/01/2023
Academic Unit: Prosthodontics
Record Identifier: 9984945915602771

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