Journal article
Use of remdesivir in the presence of elevated LFTs for the treatment of severe COVID-19 infection
BMJ case reports, Vol.13(10), p.e239210
10/01/2020
DOI: 10.1136/bcr-2020-239210
PMCID: PMC10577715
PMID: 33130588
Abstract
An 82-year-old man with an extensive medical history presented to the emergency room with complaints of generalised weakness and cough. He tested positive for COVID-19 10 days prior to presenting to the emergency room. Although his symptoms started a week prior to diagnosis, his weakness increased, warranting emergency response. A comprehensive metabolic panel was drawn from the patient on admission, indicating markedly high liver function tests (LFTs) >= 20 times above the upper limit of normal. On day 1 of admission, the decision was still made to start remdesivir (5-day course) due to decompensated acute respiratory failure as well as dexamethasone. The patient's LFTs significantly improved throughout his hospital stay. The patient made a full recovery and was discharged on day 10 of hospitalisation.
Details
- Title: Subtitle
- Use of remdesivir in the presence of elevated LFTs for the treatment of severe COVID-19 infection
- Creators
- Andrew J. Sabers - University of IowaAmber L. Williams - Univ Iowa, Coll Pharm, Pharm Practice & Sci, Iowa City, IA 52242 USAT. Michael Farley - Pharmacy Practice and Science
- Resource Type
- Journal article
- Publication Details
- BMJ case reports, Vol.13(10), p.e239210
- DOI
- 10.1136/bcr-2020-239210
- PMID
- 33130588
- PMCID
- PMC10577715
- NLM abbreviation
- BMJ Case Rep
- ISSN
- 1757-790X
- eISSN
- 1757-790X
- Publisher
- Bmj Publishing Group
- Number of pages
- 3
- Language
- English
- Date published
- 10/01/2020
- Academic Unit
- Pharmacy Practice and Science
- Record Identifier
- 9984366037702771
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