Use of the DirecNet Applied Treatment Algorithm (DATA) for diabetes management with a real-time continuous glucose monitor (the FreeStyle Navigator)

Bruce Buckingham; Dongyuan Xing; Stu Weinzimer; Rosanna Fiallo-Scharer; Craig Kollman; Nelly Mauras; Eva Tsalikian; William Tamborlane; Tim Wysocki; Katrina Ruedy; Roy Beck; Diabetes Research In Children Network (DirecNet) Study Group

doi:10.1111/j.1399-5448.2007.00301.x

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Use of the DirecNet Applied Treatment Algorithm (DATA) for diabetes management with a real-time continuous glucose monitor (the FreeStyle Navigator)

Journal article

Open access

Peer reviewed

Use of the DirecNet Applied Treatment Algorithm (DATA) for diabetes management with a real-time continuous glucose monitor (the FreeStyle Navigator)

Bruce Buckingham, Dongyuan Xing, Stu Weinzimer, Rosanna Fiallo-Scharer, Craig Kollman, Nelly Mauras, Eva Tsalikian, William Tamborlane, Tim Wysocki, Katrina Ruedy, …

Pediatric diabetes, Vol.9(2), pp.142-147

04/2008

DOI: 10.1111/j.1399-5448.2007.00301.x

PMCID: PMC2390770

PMID: 18221427

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Abstract

There are no published guidelines for use of real-time continuous glucose monitoring data by a patient; we therefore developed the DirecNet Applied Treatment Algorithm (DATA). The DATA provides algorithms for making diabetes management decisions using glucose values: (i) in real time which include the direction and rate of change of glucose levels, and (ii) retrospectively based on downloaded sensor data. To evaluate the use and effectiveness of the DATA in children with diabetes using a real-time continuous glucose sensor (the FreeStyle Navigator). Thirty children and adolescents (mean +/- standard deviation age = 11.2 +/- 4.1 yr) receiving insulin pump therapy. Subjects were instructed on use of the DATA and were asked to download their Navigator weekly to review glucose patterns. An Algorithm Satisfaction Questionnaire was completed at 3, 7, and 13 wk. At 13 wk, all of the subjects and all but one parent thought that the DATA gave good, clear directions for insulin dosing, and thought the guidelines improved their postprandial glucose levels. In responding to alarms, 86% of patients used the DATA at least 50% of the time at 3 wk, and 59% reported doing so at 13 wk. Similar results were seen in using the DATA to adjust premeal bolus doses of insulin. These results show the feasibility of implementing the DATA when real-time continuous glucose monitoring is initiated and support its use in future clinical trials of real-time continuous glucose monitoring.

Diabetes Mellitus - blood

Blood Glucose - analysis

Monitoring, Ambulatory - methods

Humans

Diabetes Mellitus - drug therapy

Feasibility Studies

Patient Satisfaction

Algorithms

Diabetes Mellitus - therapy

Adolescent

Monitoring, Physiologic - methods

Computer Systems

Insulin Infusion Systems

Blood Glucose - metabolism

Child

Details

Title: Subtitle: Use of the DirecNet Applied Treatment Algorithm (DATA) for diabetes management with a real-time continuous glucose monitor (the FreeStyle Navigator)
Creators: Bruce Buckingham
Dongyuan Xing
Stu Weinzimer
Rosanna Fiallo-Scharer
Craig Kollman
Nelly Mauras
Eva Tsalikian
William Tamborlane
Tim Wysocki
Katrina Ruedy
Roy Beck
Diabetes Research In Children Network (DirecNet) Study Group
Resource Type: Journal article
Publication Details: Pediatric diabetes, Vol.9(2), pp.142-147
DOI: 10.1111/j.1399-5448.2007.00301.x
PMID: 18221427
PMCID: PMC2390770
NLM abbreviation: Pediatr Diabetes
ISSN: 1399-543X
eISSN: 1399-5448
Grant note: U10 HD041890 / NICHD NIH HHS U10 HD041915-01 / NICHD NIH HHS U10 HD041906 / NICHD NIH HHS U10 HD041919-01 / NICHD NIH HHS U10 HD041918-01 / NICHD NIH HHS HD041890 / NICHD NIH HHS U10 HD041918 / NICHD NIH HHS U10 HD041906-01 / NICHD NIH HHS U10 HD041919 / NICHD NIH HHS U10 HD041908-01 / NICHD NIH HHS U10 HD041915 / NICHD NIH HHS U01 HD041890-01 / NICHD NIH HHS U10 HD041908 / NICHD NIH HHS UL1 RR024979 / NCRR NIH HHS U01 HD041890 / NICHD NIH HHS
Language: English
Date published: 04/2008
Academic Unit: Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center
Record Identifier: 9984093223102771

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