Journal article
Use of the Woven EndoBridge Device for Sidewall Aneurysms: Systematic Review and Meta-analysis
American journal of neuroradiology : AJNR, Vol.44(2), pp.165-170
02/2023
DOI: 10.3174/ajnr.A7766
PMCID: PMC9891330
PMID: 36635056
Abstract
The Woven EndoBridge device was originally approved to treat intracranial wide-neck saccular bifurcation aneurysms. Recent studies have suggested its use for the treatment of sidewall intracranial aneurysms with variable success.
Our aim was to evaluate the safety and efficacy of the Woven EndoBridge device for sidewall aneurysms using a meta-analysis of the literature.
We performed a systematic review of all studies including patients treated with the Woven EndoBridge device for sidewall aneurysms from inception until May 2022 on Scopus, EMBASE, MEDLINE, the Web of Science, and the Cochrane Central Register of Controlled Trials.
Ten studies were selected, and 285 patients with 288 sidewall aneurysms were included.
A random-effects meta-analysis of proportions using a generalized linear mixed model was performed as appropriate. Statistical heterogeneity across studies was assessed with I
statistics.
The adequate occlusion rate at last follow-up was 89% (95% CI, 81%-94%; I
= 0%), the composite safety outcome was 8% (95% CI, 3%-17%; I
= 34%), and the mortality rate was 2% (95% CI, 1%-7%; I
= 0%). Aneurysm width (OR = 0.5;
= .03) was the only significant predictor of complete occlusion.
Given the level of evidence, our results should be interpreted cautiously until confirmation from larger prospective studies is obtained.
The initial evidence evaluating the use of the Woven EndoBridge device for the treatment of wide-neck sidewall intracranial aneurysms has demonstrated high rates of adequate occlusion with low procedural complications. Our findings favor the consideration of the Woven EndoBridge device as an option for the treatment of sidewall aneurysms.
Details
- Title: Subtitle
- Use of the Woven EndoBridge Device for Sidewall Aneurysms: Systematic Review and Meta-analysis
- Creators
- A Rodriguez-Calienes - University of IowaJ Vivanco-Suarez - Franklin & Marshall CollegeM Galecio-Castillo - Franklin & Marshall CollegeC B Zevallos - University of Iowa, NeurologyM Farooqui - University of Iowa, NeurologyM Malaga - Franklin & Marshall CollegeC Moran-Mariños - Universidad San Ignacio de LoyolaN F Fanning - Cork University HospitalO Algin - Bilkent UniversityE A Samaniego - University of Iowa Hospitals and ClinicsB Pabon - Municipality of MedellínN Mouchtouris - Thomas Jefferson University HospitalD J Altschul - Montefiore Medical CenterP Jabbour - Thomas Jefferson University HospitalS Ortega-Gutierrez - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- American journal of neuroradiology : AJNR, Vol.44(2), pp.165-170
- DOI
- 10.3174/ajnr.A7766
- PMID
- 36635056
- PMCID
- PMC9891330
- NLM abbreviation
- AJNR Am J Neuroradiol
- ISSN
- 0195-6108
- eISSN
- 1936-959X
- Language
- English
- Electronic publication date
- 01/12/2023
- Date published
- 02/2023
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984359708502771
Metrics
23 Record Views