Journal article
Usefulness of AgNOR counts in diagnosing epithelial dysplasia
Journal of oral pathology & medicine, Vol.32(2), pp.71-76
02/2003
DOI: 10.1034/j.1600-0714.2003.00053.x
PMID: 12542828
Abstract
Diagnosis of epithelial dysplasia has traditionally been subjective, and there is a need for a quantifiable and useful test. In a double blind study, clinical leukoplakias from 52 people were diagnosed for presence (DLK) or absence (NDLK) of epithelial dysplasia using hematoxylin and eosin (H&E) stain as a gold standard criterion, and results were compared against their mean silver stainable nucleolar organizer region (AgNOR) counts. We used mean AgNOR count cut-point of 2.37 from our prior report as the diagnostic threshold (mean >or= 2.37 being DLK and mean < 2.37 being NDLK). The two methods (H&E and AgNOR) disagreed in 37% of the diagnoses. Both NDLK and DLK had high AgNOR counts. P-AgNOR was non-contributory for diagnosing epithelial dysplasia. Mean AgNOR count can be a useful tool in definitive diagnosis of epithelial dysplasia.
Details
- Title: Subtitle
- Usefulness of AgNOR counts in diagnosing epithelial dysplasia
- Creators
- Jay G Ray - Department of Oral Pathology and Microbiology, Dr R Ahmed Dental College and, Hospital, Kolkata, IndiaAmit ChattopadhyayDaniel J Caplan
- Resource Type
- Journal article
- Publication Details
- Journal of oral pathology & medicine, Vol.32(2), pp.71-76
- Publisher
- Denmark
- DOI
- 10.1034/j.1600-0714.2003.00053.x
- PMID
- 12542828
- ISSN
- 0904-2512
- eISSN
- 1600-0714
- Language
- English
- Date published
- 02/2003
- Academic Unit
- Preventive and Community Dentistry
- Record Identifier
- 9983917772702771
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