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Usefulness of Procalcitonin in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
Journal article   Open access   Peer reviewed

Usefulness of Procalcitonin in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

Donna Ann Cheung, Leonardo Tamariz, Zsuzsanna Nemeth and Amber Hamid Langshaw
Crohn's & colitis 360, Vol.1(3), otz032
10/01/2019
DOI: 10.1093/crocol/otz032
url
https://doi.org/10.1093/crocol/otz032View
Published (Version of record) Open Access

Abstract

Background: Mixed results are reported for procalcitonin (PCT) as biomarkers of infection and disease activity in inflammatory bowel disease (IBD). Method: We systematically evaluated and performed a meta-analysis on the usefulness of PCT in assessing infection and disease activity in IBD. Results: The pooled standardized mean difference of PCT for those with infection compared with those without was 1.59 (95% CI, 0.72-2.46, P < 0.01) and those with active disease compared with those without was 1.22 (95% CI, 0.66-1.78, P < 0.01), respectively. Conclusion: PCT may potentially be useful in differentiating an infectious process from IBD and active from inactive IBD.
Gastroenterology & Hepatology Life Sciences & Biomedicine Science & Technology

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