Journal article
Usefulness of blood pressure rise prior to exercise stress testing to predict the risk of future hypertension in normotensive Korean men
The American journal of cardiology, Vol.114(8), pp.1238-1242
10/15/2014
DOI: 10.1016/j.amjcard.2014.07.050
PMID: 25152425
Abstract
The aim of this study was to test the hypothesis that blood pressure (BP) increase before exercise stress testing is associated with the incidence of hypertension in a prospective study of 3,805 normotensive men without hypertension at baseline. Changes in BP were defined as the difference between seated BP at rest and BP measured immediately before exercise stress testing. Hypertension was defined as systolic and diastolic BP ≥ 140/90 mm Hg or hypertension diagnosed by a physician at the second examination. During 18,923 patient-years of follow-up, 371 new cases of hypertension developed (incidence rate 19.6 per 1,000 patient-years). Men with systolic BP changes >0 mm Hg and diastolic BP changes >7 mm Hg had 1.70 times (95% confidence interval [CI] 1.37 to 2.12) and 2.23 times (95% CI 1.76 to 2.82) increased relative risk for incident hypertension compared with men whose systolic BP changes were <0 mm Hg and diastolic BP changes were <7 mm Hg after adjustment for confounders. Men in the highest quartile of mean BP change (>10 mm Hg) had a higher incidence of hypertension (relative risk 2.98, 95% CI 2.19 to 4.06) compared with those in the lowest quartile (<0 mm Hg), and each 1 mm Hg increment in mean BP was associated with a 6% (95% CI 1.05 to 1.09) higher incidence of hypertension after adjustment for risk factors. In conclusion, BP increase before exercise stress testing is associated with incident hypertension, independent of risk factors in normotensive men. The assessment of BP immediately before exercise testing may be a useful addition to the standard exercise stress testing procedures.
Details
- Title: Subtitle
- Usefulness of blood pressure rise prior to exercise stress testing to predict the risk of future hypertension in normotensive Korean men
- Creators
- Sae Young Jae - University of SeoulSudhir Kurl - University of Eastern FinlandJari A Laukkanen - University of Eastern FinlandYoon-Ho Choi - Samsung Medical CenterWon Hah Park - Samsung Medical CenterKanokwan Bunsawat - University of Illinois Urbana-ChampaignKevin S Heffernan - Syracuse UniversityBo Fernhall - University of Illinois Urbana-ChampaignSeok-Min Kang - Yonsei UniversityJeong Bae Park - Catholic Kwandong University
- Resource Type
- Journal article
- Publication Details
- The American journal of cardiology, Vol.114(8), pp.1238-1242
- DOI
- 10.1016/j.amjcard.2014.07.050
- PMID
- 25152425
- NLM abbreviation
- Am J Cardiol
- ISSN
- 0002-9149
- eISSN
- 1879-1913
- Language
- English
- Date published
- 10/15/2014
- Academic Unit
- Health, Sport, and Human Physiology
- Record Identifier
- 9984948143302771
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