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Uses and limitations of positron emission tomography in clinical pharmacokinetics/dynamics (Part I)
Journal article   Peer reviewed

Uses and limitations of positron emission tomography in clinical pharmacokinetics/dynamics (Part I)

L L Ponto and J A Ponto
Clinical pharmacokinetics, Vol.22(3), pp.211-222
03/1992
DOI: 10.2165/00003088-199222030-00003
PMID: 1559312

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Abstract

Positron emission tomography (PET) involves imaging the biodistribution and tissue localisation of small amounts of radiolabelled biomolecules or drugs. In Part I of this article, the applications of pharmacokinetics in PET are discussed in order to derive quantitative measures of physiological function. Part II will examine the use of PET imaging as a tool to study the pharmacokinetics and pharmacodynamics of specific drugs.
Tomography, Emission-Computed - methods Pharmacokinetics Models, Biological Humans

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