Journal article
Using Computed Tomography Coronary Angiography to Differentiate Atypical Cardiac Myxoma From Thrombus
Journal of computer assisted tomography, Vol.49(4), pp.595-603
07/2025
DOI: 10.1097/RCT.0000000000001708
PMID: 40008956
Abstract
Atypical cardiac myxoma usually presents as an isolated mass attached to the atrial septum on imaging, with no movement and a wider attachment base. It is difficult to distinguish it from cardiac thrombus through conventional echocardiography or computed tomography (CT). The purpose of this study is to evaluate the value of CT coronary angiography imaging features in distinguishing atypical cardiac myxoma from cardiac thrombus.
This retrospective study included patients with atypical myxoma of the heart confirmed by histopathology (n = 18) and with thrombus disappearance after anticoagulation treatment (n = 23). All patients underwent a third-generation dual-source CT coronary angiography. We compared the clinical features and CT coronary angiography image characteristics of the 2 groups and used maximum-intensity projection and multiplanar reconstruction to show neovascularization of atypical cardiac myxoma.
There are significant differences in the origin, surface, and enhancement patterns between atypical cardiac myxoma and thrombus (P < 0.05, respectively). Specifically, supplied vessels were observed in the atypical cardiac myxoma group, while no neovascularization was detected in the thrombus group (83.33% vs. 0%, P < 0.001).
Noninvasive CT coronary angiography can help distinguish atypical cardiac myxoma and cardiac thrombus through imaging features, especially by detecting the supplying vessels. However, supplementary examinations such as cardiac magnetic resonance imaging are still needed to identify different cardiac tumors.
Details
- Title: Subtitle
- Using Computed Tomography Coronary Angiography to Differentiate Atypical Cardiac Myxoma From Thrombus
- Creators
- Nannan Zhang - Wenzhou Medical UniversityChuanqiang Lan - Wenzhou Medical UniversityZeliu Du - Wenzhou Medical UniversityGuihan Lin - Wenzhou Medical UniversityYi Zhong - Wenzhou Medical UniversityJingle Fei - Wenzhou Medical UniversityKan Liu - Washington University in St. LouisJiansong Ji - Wenzhou Medical UniversityChenying Lu - Wenzhou Medical University
- Resource Type
- Journal article
- Publication Details
- Journal of computer assisted tomography, Vol.49(4), pp.595-603
- DOI
- 10.1097/RCT.0000000000001708
- PMID
- 40008956
- NLM abbreviation
- J Comput Assist Tomogr
- ISSN
- 1532-3145
- eISSN
- 1532-3145
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Language
- English
- Electronic publication date
- 02/25/2025
- Date published
- 07/2025
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984795472202771
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