Journal article
Using guideline-directed medical therapies to improve kidney and cardiovascular outcomes in patients with chronic kidney disease
American journal of health-system pharmacy, Vol.82(12), pp.681-692
06/11/2025
DOI: 10.1093/ajhp/zxaf045
PMID: 40197743
Abstract
An estimated 37 million people currently live with chronic kidney disease in the US, which places them at increased risk for kidney disease progression, cardiovascular disease, and mortality. This review discusses current standard-of-care management of patients with chronic kidney disease, identifies key gaps in care, and briefly highlights how pharmacists can address gaps in care as members of the multidisciplinary care team.
Recent advances in guideline-directed medical therapies for patients with chronic kidney disease, including agents from the sodium-glucose cotransporter, glucagon-like peptide-1 receptor agonist, and nonsteroidal mineralocorticoid receptor antagonist classes, can dramatically improve cardiovascular-kidney-metabolic care and outcomes. Unfortunately, gaps in screening, diagnosis, and implementation of recommended therapies persist. Team-based models of care-inclusive of the person with chronic kidney disease-have the potential to significantly improve care and outcomes for people with chronic kidney disease by addressing current gaps in care.
As members of the multidisciplinary care team, pharmacists can play a critical role in addressing current gaps in care, including optimized use of guideline-directed medical therapies, in patients with chronic kidney disease.
Details
- Title: Subtitle
- Using guideline-directed medical therapies to improve kidney and cardiovascular outcomes in patients with chronic kidney disease
- Creators
- Thelma Barber - National Kidney FoundationJoshua J Neumiller - Washington State University SpokaneMichelle A Fravel - University of IowaRobert L Page II - University of Colorado Anschutz Medical CampusKatherine R Tuttle - University of Washington School of Medicine
- Resource Type
- Journal article
- Publication Details
- American journal of health-system pharmacy, Vol.82(12), pp.681-692
- DOI
- 10.1093/ajhp/zxaf045
- PMID
- 40197743
- NLM abbreviation
- Am J Health Syst Pharm
- ISSN
- 1079-2082
- eISSN
- 1535-2900
- Publisher
- OXFORD UNIV PRESS INC
- Language
- English
- Electronic publication date
- 04/08/2025
- Date published
- 06/11/2025
- Academic Unit
- Pharmacy Practice and Science
- Record Identifier
- 9984808526202771
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