Using oral vancomycin prescriptions as a proxy measure for Clostridium difficile infections: a spatial and time series analysis

Philip M Polgreen; Ming Yang; Jennifer L Kuntz; Ramanan Laxminarayan; Joseph E Cavanaugh

doi:10.1086/660858

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Using oral vancomycin prescriptions as a proxy measure for Clostridium difficile infections: a spatial and time series analysis

Journal article

Peer reviewed

Using oral vancomycin prescriptions as a proxy measure for Clostridium difficile infections: a spatial and time series analysis

Philip M Polgreen, Ming Yang, Jennifer L Kuntz, Ramanan Laxminarayan and Joseph E Cavanaugh

Infection control and hospital epidemiology, Vol.32(7), pp.723-726

07/2011

DOI: 10.1086/660858

PMCID: PMC3258488

PMID: 21666407

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https://www.ncbi.nlm.nih.gov/pmc/articles/3258488View

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Abstract

Sales for a drug may be correlated with the prevalence of a condition treated by the drug. We found that state data revealed a strong spatial association and national data a strong temporal association between Clostridium difficile and oral vancomycin prescription sales, suggesting a new "signal" for detecting disease activity.

Vancomycin - administration & dosage

Administration, Oral

Humans

Clostridium difficile

Linear Models

Clostridium Infections - epidemiology

Anti-Bacterial Agents - therapeutic use

Drug Prescriptions - statistics & numerical data

Vancomycin - therapeutic use

Clostridium Infections - drug therapy

Ohio - epidemiology

Seasons

Anti-Bacterial Agents - administration & dosage

Drug Utilization - statistics & numerical data

Population Surveillance - methods

Cluster Analysis

Details

Title: Subtitle: Using oral vancomycin prescriptions as a proxy measure for Clostridium difficile infections: a spatial and time series analysis
Creators: Philip M Polgreen - Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA. philip-polgreen@uiowa.edu
Ming Yang
Jennifer L Kuntz
Ramanan Laxminarayan
Joseph E Cavanaugh
Resource Type: Journal article
Publication Details: Infection control and hospital epidemiology, Vol.32(7), pp.723-726
DOI: 10.1086/660858
PMID: 21666407
PMCID: PMC3258488
NLM abbreviation: Infect Control Hosp Epidemiol
ISSN: 0899-823X
eISSN: 1559-6834
Publisher: United States
Grant note: K01 AI75089 / NIAID NIH HHS K01 AI075089-04 / NIAID NIH HHS K01 AI075089 / NIAID NIH HHS
Language: English
Date published: 07/2011
Academic Unit: Statistics and Actuarial Science; Infectious Diseases; Epidemiology; Biostatistics; Injury Prevention Research Center; Internal Medicine
Record Identifier: 9983985889702771

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