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Using solution-phase nanoparticles, surface-confined nanoparticle arrays and single nanoparticles as biological sensing platforms
Journal article   Peer reviewed

Using solution-phase nanoparticles, surface-confined nanoparticle arrays and single nanoparticles as biological sensing platforms

Amanda J Haes, Douglas A Stuart, Shuming Nie and Richard P Van Duyne
Journal of fluorescence, Vol.14(4), pp.355-367
07/2004
DOI: 10.1023/B:JOFL.0000031817.35049.1f
PMID: 15617378

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Abstract

The intense colors of noble metal nanoparticles have inspired artists and fascinated scientists for hundreds of years. In this review, we describe three sensing platforms based on the tunability of the localized surface plasmon resonance (LSPR) of gold and silver nanoparticles. Specifically, the color associated with solution-phase nanoparticles, surface-confined nanoparticle arrays, and single nanoparticles will be shown to be tunable and useful as platforms for biological sensing.
Gold - chemistry Silver - chemistry Colorimetry Surface Plasmon Resonance - methods Bacterial Proteins - analysis Biotin - analysis Solutions - chemistry Algorithms Streptavidin - metabolism Streptavidin - analysis Antibodies - immunology Nanostructures - chemistry Biosensing Techniques - methods Biotin - metabolism Biotin - immunology Spectrophotometry Biotin - analogs & derivatives

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