Journal article
Using structural equation model to illustrate the relationship between metabolic risk factors and cardiovascular complications in Taiwan
European journal of cardiovascular prevention and rehabilitation, Vol.13(4), pp.633-639
08/2006
DOI: 10.1097/01.hjr.0000230095.65062.a9
PMID: 16874156
Abstract
Background: The objective of this study was to perform a population-based screening programme to determine the prevalence of the metabolic syndrome (MetS) and the relationship between metabolic risk factors and prevalent cardiovascular complications in Taiwan.
Design: A screening programme recruited residents aged 40 years and older in Sanchih, Taipei County, Taiwan, and collected demographic data, blood and urine samples. Fasting plasma glucose level, serum total cholesterol, high-density lipoprotein cholesterol, and triglyceride were measured. Atherosclerotic complications, including myocardial infarction, stress-positive angina, ischaemic stroke, and proteinuria were confirmed.
Methods: A structural equation model (SEM) was constructed to identify the association between metabolic abnormality and atherosclerosis.
Results: A total of 1494 subjects, 776 male and 718 female, were recruited in this study. The crude prevalence of the MetS was 19.3% for men [95% confidence interval (CI) 16.3-22.2%] and 18.7% for women (95% CI 15.6-22.0%). The presence of the MetS posed a substantial risk to microvascular complications in both sexes [odds ratio (OR) 3.29, P<0.001] and to macrovascular complications in men (OR 1.95, P=0.04) and also a trend in women (OR 2.24, P=0.089). There was a positive association between metabolic abnormality and atherosclerosis (B=0.55, P<0.001).
Conclusions: This study has found the prevalence of the MetS and the association with atherosclerotic complications in Taiwan. The SEM approach has demonstrated a positive correlation between metabolic abnormality and atherosclerosis and can be used to explore new risk factors for cardiovascular diseases.
Details
- Title: Subtitle
- Using structural equation model to illustrate the relationship between metabolic risk factors and cardiovascular complications in Taiwan
- Creators
- Jou-Wei Lin - National Taiwan University Hospital Yun-Lin Branch, Yun-LinJuey-Jen Hwang - National Taiwan University Hospital Yun-Lin Branch, Yun-LinDao-Fu Dai - National Taiwan University Hospital, Taipei, TaiwanYung-Zu Tseng - National Taiwan University Hospital, Taipei, Taiwan
- Resource Type
- Journal article
- Publication Details
- European journal of cardiovascular prevention and rehabilitation, Vol.13(4), pp.633-639
- DOI
- 10.1097/01.hjr.0000230095.65062.a9
- PMID
- 16874156
- ISSN
- 1741-8267
- eISSN
- 1741-8275
- Language
- English
- Date published
- 08/2006
- Academic Unit
- Pathology; Iowa Neuroscience Institute; Radiation Oncology
- Record Identifier
- 9984047774202771
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