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Using the Electronic Health Record to Facilitate Drug Allergy Delabeling
Journal article   Open access   Peer reviewed

Using the Electronic Health Record to Facilitate Drug Allergy Delabeling

Matthew J Molloy, Adam P Yan, Averi E Wilson, Jonathan Beus and Lauren M Hess
Current allergy and asthma reports, Vol.25(1), p.49
10/25/2025
DOI: 10.1007/s11882-025-01229-2
PMCID: PMC12552388
PMID: 41136878
url
https://doi.org/10.1007/s11882-025-01229-2View
Published (Version of record) Open Access

Abstract

There is a growing number of allergy delabeling programs across diverse clinical specialties and care settings. The electronic health record (EHR) can be leveraged to facilitate allergy delabeling. The purpose of this review is to describe EHR tools that have been used in allergy delabeling programs. We also provide recommendations for organizations considering EHR-based allergy delabeling workflows that incorporate clinical informatics best practices. Recent literature describes several EHR tools used in delabeling. These tools can be organized around the steps of the allergy delabeling workflow: 1. Identify eligible patients, 2. Risk stratify, 3. Evaluation and testing, 4. Documentation of outcome, 5. Delabeling, and 6. Allergy label reconciliation. Standardized EHR tools across the allergy delabeling workflow can lead to successful delabeling and support of diverse stakeholders. Partnering with EHR vendors presents an opportunity to make these tools readily available and improve allergy documentation.
Documentation Drug Hypersensitivity - diagnosis Electronic Health Records Humans Workflow

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