Uterine sarcoma: a clinicopathological study of 93 cases

E González-Bosquet; J M Martínez-Palones; J González-Bosquet; A García Jiménez; J Xercavins

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Journal article

Uterine sarcoma: a clinicopathological study of 93 cases

E González-Bosquet, J M Martínez-Palones, J González-Bosquet, A García Jiménez and J Xercavins

European journal of gynaecological oncology, Vol.18(3), pp.192-195

1997

PMID: 9174834

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Abstract

To evaluate the clinical outcome of patients suffering from primary uterine sarcoma diagnosed and treated in our Hospital. Department of Gynecologic Surgery/Gynecologic Oncology, Hospital Universitario Materno-Infantil Vall d'Hebron de Barcelona, Barcelona, Spain. A retrospective review from 1967 to 1995 of clinical and pathological characteristics of 93 patients with primary uterine sarcoma was done. Patients were staged using the 1988 FIGO histological classification for uterine cancer. Clinical features, type of surgery, adjuvant therapy, recurrences, distant metastasis, and survival were recorded. Our study included three main histologic types: 44 patients with leiomyosarcoma, 26 patients with endometrial stromal sarcoma, and 18 patients with mixed Müllerian sarcomas. The mean age for all patients was 54.8 years, and the most common symptom was vaginal bleeding. Other clinicopathological features were examined. Although surgery was the most frequent treatment, adjuvant therapies have been analyzed and discussed. The overall three-year survival rate was 67.9% and the overall five-year survival rate was 64.5%. We found statistical differences (p < 0.001) between the stage I survival rate and other stage survival rates. Uterine sarcoma is an uncommon neoplasia diagnosed in the 6th decade of life. Leiomyosarcoma is the most frequent histologic type (47.3%). Stage I uterine sarcoma has a better prognosis than other stages.

Uterine Neoplasms - therapy

Diagnosis, Differential

Prognosis

Leiomyosarcoma - pathology

Uterine Neoplasms - pathology

Humans

Middle Aged

Sarcoma, Endometrial Stromal - therapy

Survival Rate

Combined Modality Therapy

Mixed Tumor, Mesodermal - pathology

Mixed Tumor, Mesodermal - therapy

Sarcoma, Endometrial Stromal - mortality

Leiomyosarcoma - therapy

Mixed Tumor, Mesodermal - mortality

Sarcoma, Endometrial Stromal - pathology

Leiomyosarcoma - mortality

Uterine Neoplasms - mortality

Adult

Female

Aged

Retrospective Studies

Neoplasm Staging

Evaluation Studies as Topic

Details

Title: Subtitle: Uterine sarcoma: a clinicopathological study of 93 cases
Creators: E González-Bosquet - Department of Gynecologic Surgery/Gynecologic Oncology, Hospital Universitario Materno-Infantil Vall d'Hebron, Barcelona, Spain
J M Martínez-Palones
J González-Bosquet
A García Jiménez
J Xercavins
Resource Type: Journal article
Publication Details: European journal of gynaecological oncology, Vol.18(3), pp.192-195
Publisher: Italy
PMID: 9174834
ISSN: 0392-2936
Language: English
Date published: 1997
Academic Unit: Obstetrics and Gynecology
Record Identifier: 9983931828302771

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